Key Insights

Highlights

Success Rate

92% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 30/100

Termination Rate

4.3%

1 terminated out of 23 trials

Success Rate

91.7%

+5.2% vs benchmark

Late-Stage Pipeline

30%

7 trials in Phase 3/4

Results Transparency

27%

3 of 11 completed with results

Key Signals

3 with results92% success

Data Visualizations

Phase Distribution

19Total
Not Applicable (9)
P 1 (1)
P 2 (2)
P 3 (4)
P 4 (3)

Trial Status

Completed11
Unknown7
Recruiting2
Not Yet Recruiting1
Withdrawn1
Terminated1

Trial Success Rate

91.7%

Benchmark: 86.5%

Based on 11 completed trials

Clinical Trials (23)

Showing 20 of 20 trials
NCT07095361Phase 4Recruiting

Once Daily Intrapleural Enzyme Therapy in Complicated Parapneumonic Effusion or Empyema

NCT04350502Not ApplicableCompleted

Pharmacokinetics and Pleural Fluid Penetration of Amoxicillin and Clavulanic Acid in Patients With Pleural Infections

NCT05620329Recruiting

UNC Pleural Fluid Registry

NCT06235359Not ApplicableNot Yet RecruitingPrimary

Is Intercostal Tube Enough in Management of Empyema

NCT06132997Not ApplicableUnknownPrimary

Medical Thoracoscopy in Treatment Outcomes of Empyema Management

NCT03167723Not ApplicableCompleted

Prospective Evaluation of 14F Thal Tube vs 28 French Chest Tube for Hemothorax and Use of Maximum Barrier Precautions

NCT03468933Phase 4Completed

Fibrinolysis Compared to Thoracoscopy for Pleural Infection

NCT04695275UnknownPrimary

Clinical Feature and Microbiology Characteristics of Empyema in Children

NCT04193241Not ApplicableUnknown

Suturing With U-Technique Versus Un-Reapproximated Wound Edges During Removal of Closed Thoracostomy Tube Drain

NCT02014077Not ApplicableCompleted

VATS ( Video-Assisted Thoracoscopy) Compared to Reinsertion of a Thoracostomy Tube for Persistent Haemothorax

NCT03859206Not ApplicableUnknownPrimary

Medical Thoracoscopy Versus Tube Thoracostomy in Management of Empyema .

NCT01287013Not ApplicableTerminated

Comparing Xperguide vs. Conventional Methods During Percutaneous Image Guided Procedures

NCT02446782Phase 4Completed

Efficacy and Safety of Prophylactic Use of an Antibiotic for Medical Thoracoscopy

NCT01862458Phase 3WithdrawnPrimary

Empyema Treated With tPA & DNAse

NCT01261546Phase 2Completed

Clinical Trial Corticoids For Empyema And Pleural Effusion In Children

NCT01522885Phase 3Completed

KatGuide Method Versus Conventional Method at Insertion of Chest Tube

NCT01625247Phase 3Unknown

Drainage is Not Necessary Procedure After Laparoscopic Cholecystectomy Due to Severe Acute Cholecystitis

NCT01178580Completed

Procoagulant Activity in Patients With Community Acquired Pneumonia, Pleural Effusion and Empyema

NCT00798278Phase 3CompletedPrimary

Urokinase Versus Video-assisted Thoracoscopic to Treat Complicated Parapneumonic Empyema in Childhood

NCT00323531Phase 2CompletedPrimary

Thoracoscopy Versus Fibrinolysis in Children With Empyema

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Research Network

Activity Timeline