Key Insights

Highlights

Success Rate

71% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

4.8%

2 terminated out of 42 trials

Success Rate

71.4%

-15.1% vs benchmark

Late-Stage Pipeline

10%

4 trials in Phase 3/4

Results Transparency

0%

0 of 5 completed with results

Key Signals

71% success

Data Visualizations

Phase Distribution

36Total
Not Applicable (6)
Early P 1 (2)
P 1 (8)
P 2 (16)
P 3 (1)
P 4 (3)

Trial Status

Unknown16
Recruiting7
Not Yet Recruiting6
Completed5
Active Not Recruiting5
Terminated2

Trial Success Rate

71.4%

Benchmark: 86.5%

Based on 5 completed trials

Clinical Trials (42)

Showing 20 of 20 trials
NCT07298148Phase 2Not Yet Recruiting

Firmonertinib 160 mg in Patients With EGFR-Mutant Advanced NSCLC Demonstrating SD After 8 Week Induction With Firmonertinib 80 mg

NCT05089916Phase 2Active Not Recruiting

Radiation During Osimertinib Treatment: a Safety and Efficacy Cohort Study

NCT07322783Phase 2RecruitingPrimary

Osimertinib Combined With Savolitinib in the Treatment of NSCLC With Low Copy Number MET Amplification

NCT05256290Phase 1Active Not Recruiting

Phase 1/2 Study of Silevertinib (BDTX-1535) in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations

NCT04900935Not ApplicableRecruiting

Patient-centered, Optimal Integration of Survivorship and Palliative Care

NCT07239102CompletedPrimary

Firmonertinib in the Treatment of EGFR(+) NSCLC Patients With Central Nervous System Metastasis

NCT04001777Phase 1Active Not RecruitingPrimary

A Study of APG-1252 Plus Osimertinib(AZD9291) in EGFR TKI Resistant NSCLC Patients

NCT05037331RecruitingPrimary

Osimertinib for Advanced EGFR-positive NSCLC Patients

NCT04504071Phase 2Active Not Recruiting

Dacomitinib in Lung Cancer With Uncommon EGFR Mutations

NCT04027647Phase 2Active Not Recruiting

Phase 2 Study of Dacomitinib in NSCLC

NCT04862780Phase 1Terminated

(SYMPHONY) Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLC

NCT06557096Early Phase 1Not Yet Recruiting

CSF CTC-Capture-Guided EGFR-TKI and Bevacizumab Combination Therapy in EGFR-Mutant Advanced NSCLC

NCT06109558Phase 1Recruiting

The Efficacy and Safety of LMV-12 Combined With Osimertinib in NSCLC

NCT06287593Not ApplicableNot Yet RecruitingPrimary

The Feasibility of Dynamic Liquid Biopsy Monitoring During Neoadjuvant Treatment for EGFR-mutated NSCLC

NCT06352502RecruitingPrimary

An Observational Study of Furmonertinib for EGFR Mutation-positive NSCLC Patients With Brain Metastasis

NCT05573373Phase 1Unknown

Pamiparib (BGB-290) Was Used in EGFR-TkIs Resistant Non-small Cell Lung Cancer

NCT06208033Early Phase 1UnknownPrimary

SMET12 and Toripalimab Combined Chemotherapy in Patients With EGFR Positive Advanced Non-small Cell Lung Cancer (NSCLC)

NCT06207292Not ApplicableUnknown

Stereotactic Ablative Radiotherapy in Synchronous and Metachronous Oligo-Metastatic Non Small Cell Lung Cancer

NCT04105153CompletedPrimary

Real-world Analysis of Workup at Disease Progression and Implementation of Osimertinib for EGFR+ NSCLC

NCT02729298Phase 1Completed

First-in-human Study of Oral TP-0903 (a Novel Inhibitor of AXL Kinase) in Patients With Advanced Solid Tumors

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