Key Insights

Highlights

Success Rate

96% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

2.6%

1 terminated out of 38 trials

Success Rate

96.0%

+9.5% vs benchmark

Late-Stage Pipeline

16%

6 trials in Phase 3/4

Results Transparency

29%

7 of 24 completed with results

Key Signals

7 with results96% success

Data Visualizations

Phase Distribution

23Total
Not Applicable (8)
Early P 1 (1)
P 1 (6)
P 2 (2)
P 3 (5)
P 4 (1)

Trial Status

Completed24
Recruiting8
Enrolling By Invitation2
Terminated1
Unknown1
Withdrawn1

Trial Success Rate

96.0%

Benchmark: 86.5%

Based on 24 completed trials

Clinical Trials (38)

Showing 20 of 20 trials
NCT00359684RecruitingPrimary

Use of Cysteamine in the Treatment of Cystinosis

NCT05994534Phase 1RecruitingPrimary

PK and PD Study of NPI-001 and Cysteamine Bitartrate

NCT00822250Not ApplicableCompletedPrimary

Clinical and Biological Study of Sub-pigmentation During Infantile Cystinosis

NCT05901077RecruitingPrimary

European Cystinosis Cohort

NCT03897361Phase 1Completed

Stem Cell Gene Therapy for Cystinosis

NCT07319091Not ApplicableNot Yet RecruitingPrimary

Cystinosis and Mitochondrial Metabolism

NCT02012114Not ApplicableCompletedPrimary

A Cohort of Patients With Cystinosis : Compliance to Cysteamine and Neurological Complications

NCT05545774CompletedPrimary

Neuromuscular Characterisation in Late Adolescent and Adult Cystinosis Patients

NCT05687474Completed

Baby Detect : Genomic Newborn Screening

NCT01793168Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

NCT03655223Enrolling By Invitation

Early Check: Expanded Screening in Newborns

NCT01733316Phase 3CompletedPrimary

Open-Label, Safety and Superior Effectiveness Study of Cysteamine Bitartrate Delayed-Release Capsules (RP103) in Cystinosis

NCT01197378Phase 3CompletedPrimary

Long-Term Safety Follow-up Study of Cysteamine Bitartrate Delayed-release Capsules (RP103)

NCT01744782Phase 3CompletedPrimary

Safety/Effectiveness Study of Cysteamine Bitartrate Delayed-release Capsules (RP103) in Cysteamine Treatment Naive Patients With Cystinosis

NCT01000961Phase 3CompletedPrimary

Phase 3 Study of Cysteamine Bitartrate Delayed-release (RP103) Compared to Cystagon® in Patients With Cystinosis

NCT00872729Phase 1CompletedPrimary

Pilot Study of Safety, Tolerability, Pharmacokinetics/Pharmacodynamics of RP103 Compared to Cystagon® in Patients With Cystinosis

NCT04071548Not ApplicableCompletedPrimary

The Effect of Exercise on Muscle Dysfunction in Cystinosis

NCT05959668RecruitingPrimary

Development of Health-related Quality of Life Instrument for Patients With Cystinosis

NCT05146830Enrolling By InvitationPrimary

A Long-Term Follow-Up Study of Participants With Cystinosis Who Previously Received CTNS-RD-04

NCT04125927Phase 3CompletedPrimary

Cystadrops in Pediatric Cystinosis Patients From Six Months to Less Than Two Years Old (SCOB2)

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Research Network

Activity Timeline