Key Insights

Highlights

Success Rate

70% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

15.0%

3 terminated out of 20 trials

Success Rate

70.0%

-16.5% vs benchmark

Late-Stage Pipeline

20%

4 trials in Phase 3/4

Results Transparency

29%

2 of 7 completed with results

Key Signals

2 with results70% success

Data Visualizations

Phase Distribution

15Total
Not Applicable (6)
P 1 (4)
P 2 (1)
P 3 (4)

Trial Status

Completed7
Unknown4
Terminated3
Active Not Recruiting2
Recruiting2
Enrolling By Invitation1

Trial Success Rate

70.0%

Benchmark: 86.5%

Based on 7 completed trials

Clinical Trials (20)

Showing 20 of 20 trials
NCT05208905Not ApplicableActive Not RecruitingPrimary

LIFE-BTK PK Sub-study

NCT04227899Not ApplicableActive Not RecruitingPrimary

LIFE-BTK Randomized Controlled Trial

NCT07136883Not ApplicableCompleted

DCB Outcomes After Plain or Scoring Balloon for Vessel Preparation in Patients With Femoropopliteal Arterial Disease

NCT07023965Enrolling By Invitation

Follow-up Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-L)

NCT07006467Not ApplicableRecruitingPrimary

Initial Feasibility Study of the STENTiT Resorbable Fibrillated Scaffold (RFS). The RFS is Intended to Restore Lumen Patency and Blood Flow to Infrapopliteal Arteries. The RFS is a Fully Electrospun Tubular Device With a Fibrillated Microarchitecture and Designed for Transcatheter Delivery

NCT07052435Recruiting

Pressure (Fractional Flow Reserve) and Flow (Vascular Flow Reserve) Measurements During Peripheral Arterial Interventions

NCT07014072Not ApplicableNot Yet RecruitingPrimary

Comprehensive Limb Evaluation and Arterial Revascularization With Toe Pressure Optimization Registry

NCT06913348CompletedPrimary

Ultrasound-Guided Sciatic Popliteal Nerve Block vs. Erector Spinae Plane Block in Endovascular Management of CLI

NCT03886506UnknownPrimary

Expanded Access Treatment of Subjects With Critical Limb Ischemia (CLI) With Minor Tissue Loss Who Are Unsuitable for Revascularization

NCT03006770Phase 3CompletedPrimary

Efficacy, Tolerability and Safety of Intramuscular Injections of PLX PAD for the Treatment of Subjects With Critical Limb Ischemia (CLI) With Minor Tissue Loss Who Are Unsuitable for Revascularization

NCT03174522Phase 3Terminated

The Efficacy and Safety of REX-001 to Treat Ischemic Ulcers in Subjects With CLI Rutherford Category 5 and DM

NCT04849325Not ApplicableUnknownPrimary

IBS Titan vs. PTA in Patients With Infrapopliteal Arterial Stenosis or Occlusive Disease

NCT03111238Phase 3Terminated

The Efficacy and Safety of REX-001 to Treat Ischemic Rest Pain in Subjects With CLI Rutherford Category 4 and DM

NCT03746899UnknownPrimary

Expanded Access for Treatment Use of PLX-PAD in Critical Limb Ischemia (CLI)

NCT02287974Phase 1TerminatedPrimary

Clinical Trial I/II Opened, Randomized and Controlled for the Study of the Use of Stem Cells Therapy in Insulinized Diabetic Patients Type 2 With Critical Ischemia in Lower Limbs (CLI): Study of the Needs of Insulin

NCT01386216Phase 1CompletedPrimary

Safety Study of Bone Marrow Cell Concentrate Prepared Using the Magellan System to Treat Critical Limb Ischemia (CLI)

NCT02538978Phase 3UnknownPrimary

Critical Limb Ischemia Rapid Delivery by SurgWerks-CLI Kit and VXP System

NCT01408381Phase 2CompletedPrimary

Intra-arterial Infusion of Autologous Bone Marrow Mononuclear Cells in Non-diabetic Patients With Critical Limb Ischemia (CLI).

NCT00987363Phase 1CompletedPrimary

Intraarterial Infusion of Autologous Bone Marrow in Diabetic Patients With Chronic Ischemia of Lower Limbs (CLI) no Revascularization

NCT01257776Phase 1CompletedPrimary

Human Adipose Derived Mesenchymal Stem Cells for Critical Limb Ischemia (CLI) in Diabetic Patients

Showing all 20 trials

Research Network

Activity Timeline