Key Insights

Highlights

Success Rate

78% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 42/100

Termination Rate

9.1%

2 terminated out of 22 trials

Success Rate

77.8%

-8.7% vs benchmark

Late-Stage Pipeline

27%

6 trials in Phase 3/4

Results Transparency

0%

0 of 7 completed with results

Key Signals

78% success

Data Visualizations

Phase Distribution

17Total
Not Applicable (9)
P 2 (2)
P 3 (3)
P 4 (3)

Trial Status

Unknown8
Completed7
Recruiting3
Terminated2
Withdrawn1
Not Yet Recruiting1

Trial Success Rate

77.8%

Benchmark: 86.5%

Based on 7 completed trials

Clinical Trials (22)

Showing 20 of 20 trials
NCT03381794RecruitingPrimary

The German Keratoplasty Registry of the German Ophthalmological Society (DOG)

NCT05210478Not Yet RecruitingPrimary

Intraoperative Optical Coherence Tomography for Ophthalmic Surgical Guidance - Cornea

NCT03461978Not ApplicableCompleted

Ultrahigh-resolution Optical Coherence Tomography Imaging of the Anterior Eye Segment Structures

NCT05870566Not ApplicableRecruitingPrimary

Pretreatment to Promote Graft Survival After Subsequent High-risk Corneal Transplantation [CrossCornealVision]

NCT02084745Not ApplicableRecruitingPrimary

Timing of Glaucoma Drainage Device With Boston Keratoprosthesis

NCT04337944Not ApplicableUnknownPrimary

Endoscopic Assisted Anterior Hyaloid Peeling in Boston Type 1 Keratoprosthesis (KPro-HP-Endo)

NCT04339907Not ApplicableUnknown

Inflammatory Mediators of Glaucoma After Corneal Transplantation (AH-Tears)

NCT04490902Not ApplicableUnknownPrimary

Clinical Study on the Treatment of Mixed Component Cornea for High Risk Keratoplasty

NCT00345020WithdrawnPrimary

Deep Lamellar Endothelial Keratoplasty: Small Incision Technique

NCT03105466Not ApplicableUnknownPrimary

Prospective Study of Deep Anterior Lamellar Keratoplasty Using Acellular Porcine Cornea

NCT01694914Phase 3CompletedPrimary

Comparative Study of Two Corneal Graft Storage Media: New Animal Compound Free Medium Versus Reference Medium

NCT01018888Phase 4UnknownPrimary

Safety and Efficacy Study of Artificial Cornea

NCT00447642Phase 3TerminatedPrimary

Study to Assess LX201 for Prevention of Corneal Allograft Rejection or Graft Failure in Subjects Who Have Experienced One or More Rejection Episodes Following Penetrating Keratoplasty

NCT01547975CompletedPrimary

Retrospective Analysis of Surgical Outcomes After Corneal Transplantation

NCT01206127Not ApplicableUnknownPrimary

DSAEK- Postoperative Positioning and Transplant Dislocation

NCT00874835Phase 2UnknownPrimary

Corneal Endothelium Delivery Instrument

NCT00000137Phase 3CompletedPrimary

Collaborative Corneal Transplantation Studies (CCTS)

NCT00834782UnknownPrimary

Comparison of DCT, ORA and GAT in Eyes After Penetrating Keratoplasty

NCT00764582Phase 4TerminatedPrimary

Ocular Penetration of 1.5% Levofloxacin and 0.5% Moxifloxacin During Corneal Transplant Surgery

NCT00570648Not ApplicableCompletedPrimary

A Prospective Study of the Effect of Topical Sodium Hyaluronate Immediately Post-PKP on Time to Reepithelialization

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Research Network

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