Key Insights

Highlights

Success Rate

92% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 5/100

Termination Rate

4.5%

1 terminated out of 22 trials

Success Rate

91.7%

+5.2% vs benchmark

Late-Stage Pipeline

27%

6 trials in Phase 3/4

Results Transparency

73%

8 of 11 completed with results

Key Signals

8 with results92% success

Data Visualizations

Phase Distribution

19Total
P 1 (4)
P 2 (9)
P 3 (5)
P 4 (1)

Trial Status

Completed11
Recruiting4
Unknown3
Active Not Recruiting2
Withdrawn1
Terminated1

Trial Success Rate

91.7%

Benchmark: 86.5%

Based on 11 completed trials

Clinical Trials (22)

Showing 20 of 20 trials
NCT04205604Phase 2RecruitingPrimary

18FluoroLDOPA PET Imaging for the Detection and Localization of Focal Congenital Hyperinsulinism

NCT04706910Phase 3RecruitingPrimary

18F-DOPA II - PET Imaging Optimization

NCT03941236Phase 3Active Not RecruitingPrimary

Extension Trial Evaluating the Long-term Safety and Efficacy of Dasiglucagon in Children With Congenital Hyperinsulinism

NCT06208215Phase 3Active Not RecruitingPrimary

RZ358 Treatment for Congenital Hyperinsulinism

NCT04538989Phase 2CompletedPrimary

An Open-Label Multiple Dose Study of RZ358 in Patients With Congenital Hyperinsulinism

NCT04172441Phase 2CompletedPrimary

Trial Evaluating Efficacy and Safety of Dasiglucagon in Children With Congenital Hyperinsulinism

NCT04732416Phase 2RecruitingPrimary

HM15136 (Efpegerglucagon) Treatment for 8 Weeks in Subjects Aged ≥2 Years With Congenital Hyperinsulinism (CHI)

NCT02021604Phase 1RecruitingPrimary

Fluorodopa F 18 in Congenital Hyperinsulinism and Insulinoma

NCT01070758Phase 4CompletedPrimary

Lanreotide Autogel Treatment of Patients With Congenital Hyperinsulinism of Infancy

NCT03777176Phase 3CompletedPrimary

A Two-Period Open-label Trial Evaluating Efficacy and Safety of Dasiglucagon in Children With Congenital Hyperinsulinism

NCT00674440Phase 2CompletedPrimary

Utility of [F-18] fluoroDOPA for Neonatal Hyperinsulinism

NCT02835131UnknownPrimary

Compassionate Use of SOM230 for Hyperinsulinemic/Hypoglycemia

NCT03042416Phase 3CompletedPrimary

18F-DOPA PET Imaging: an Evaluation of Biodistribution and Safety

NCT03053284Phase 2WithdrawnPrimary

Pasireotide in Hyperinsulinemic Hypoglycemia

NCT02533219Unknown

Study of the Use of [18F]-DOPA in Hyperinsulinemic Hypoglycemia

NCT00835328Phase 1TerminatedPrimary

Effect of Exendin (9-39) on Glucose Requirements to Maintain Euglycemia

NCT00897676Phase 1CompletedPrimary

Effect of Exendin-(9-39) on Fasting Adaptation and Protein Sensitivity

NCT02937558Phase 2CompletedPrimary

CSI-Glucagon for Prevention of Hypoglycemia in Children With Congenital Hyperinsulinism

NCT03768518UnknownPrimary

GLP-1 Receptor Expression in CHI

NCT00571324Phase 1CompletedPrimary

Effect of Exendin-(9-39) on Glycemic Control in Subjects With Congenital Hyperinsulinism

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Research Network

Activity Timeline