Key Insights

Highlights

Success Rate

33% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

12.5%

2 terminated out of 16 trials

Success Rate

33.3%

-53.2% vs benchmark

Late-Stage Pipeline

13%

2 trials in Phase 3/4

Results Transparency

200%

2 of 1 completed with results

Key Signals

2 with results33% success

Data Visualizations

Phase Distribution

15Total
Not Applicable (2)
Early P 1 (1)
P 1 (1)
P 2 (9)
P 3 (2)

Trial Status

Recruiting7
Not Yet Recruiting2
Active Not Recruiting2
Terminated2
Completed1
Unknown1

Trial Success Rate

33.3%

Benchmark: 86.5%

Based on 1 completed trials

Clinical Trials (16)

Showing 16 of 16 trials
NCT06532279Phase 2Recruiting

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

NCT07441681Phase 3Not Yet Recruiting

Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive Cisplatin

NCT03952585Phase 2Active Not Recruiting

De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer

NCT03811015Phase 3Active Not RecruitingPrimary

Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

NCT07195734Phase 2RecruitingPrimary

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

NCT03799445Phase 2Terminated

Ipilimumab, Nivolumab, and Radiation Therapy in Treating Patients With HPV Positive Advanced Oropharyngeal Squamous Cell Carcinoma

NCT03010150Recruiting

Blood Tests and Questionnaires in Studying Adherence to Preventative Swallowing Exercises in Participants With Metastatic Head and Neck Cancer

NCT06323460Phase 2Recruiting

Adaptive De-intensified Radiotherapy Using Circulating Tumor DNA in HPV- Associated Oropharyngeal Cancer

NCT05541016Phase 2Recruiting

De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNA

NCT06914999Early Phase 1Recruiting

Comparing an Investigational Scan (F-18 NaF PET/CT) to Standard of Care Imaging (F-18 FDG PET/CT) for Evaluating Vascular Complications in Patients Receiving Radiation Therapy for Head and Neck Cancer

NCT07178301Phase 2Not Yet Recruiting

Evaluating a Decreased Dose of Radiation Therapy to the Elective Neck for the Treatment of HPV-Related Oropharyngeal Cancer, ENLIGHT Trial

NCT04900623Phase 2Recruiting

Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study

NCT04140513Not ApplicableWithdrawnPrimary

Digital PET Scan for the Prediction of Outcomes in Patients With Locally Advanced Oropharyngeal Cancer

NCT04489212Not ApplicableCompleted

Study of Mucosal Sparing Adjuvant Radiotherapy After Surgical Exploration in HPV+ Head and Neck Cancer of Unknown Primaries

NCT03618134Phase 1Terminated

Stereotactic Body Radiation Therapy and Durvalumab With or Without Tremelimumab Before Surgery in Treating Participants With Human Papillomavirus Positive Oropharyngeal Squamous Cell Caner

NCT04920344Phase 2Unknown

Swallowing Outcomes and Circulating Tumor DNA in Patients With HPV Related Oropharyngeal Cancer Treated With Transoral Surgery and Reduced Intensity Adjuvant Therapy

Showing all 16 trials

Research Network

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