Key Insights

Highlights

Success Rate

67% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

15.4%

4 terminated out of 26 trials

Success Rate

66.7%

-19.8% vs benchmark

Late-Stage Pipeline

4%

1 trials in Phase 3/4

Results Transparency

88%

7 of 8 completed with results

Key Signals

7 with results67% success

Data Visualizations

Phase Distribution

23Total
Not Applicable (4)
P 1 (4)
P 2 (14)
P 3 (1)

Trial Status

Completed8
Active Not Recruiting6
Terminated4
Unknown4
Recruiting2
Not Yet Recruiting1

Trial Success Rate

66.7%

Benchmark: 86.5%

Based on 8 completed trials

Clinical Trials (26)

Showing 20 of 20 trials
NCT07539220Not ApplicableNot Yet RecruitingPrimary

Establishment of Biomarker Panel For Forecasting Chronic Graft-Versus-Host Disease (cGVHD) After Allo-HSCT

NCT02669251Phase 1Active Not Recruiting

Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation

NCT06688942Not ApplicableActive Not RecruitingPrimary

Digital Health Intervention to Promote Quality of Life in Adults With Chronic Graft Versus Host Disease

NCT02611180Active Not Recruiting

Dendritic Cells in Patients With Acute or Chronic Skin Graft Versus Host Disease

NCT01366092Phase 2Active Not RecruitingPrimary

Daily IL-2 for Steroid-Refractory Chronic Graft-versus-Host-Disease

NCT07138196Phase 1RecruitingPrimary

A Study to Evaluate Adrixetinib (Q702) in Adults With Active Chronic Graft-Versus-Host Disease

NCT05690971Not ApplicableActive Not RecruitingPrimary

Psychosocial Mobile App for Chronic Graft-Versus-Host Disease

NCT03584516Phase 2TerminatedPrimary

GRAVITAS-309: Itacitinib and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

NCT06458127Not ApplicableActive Not RecruitingPrimary

Tele-Palliative Care Intervention for Patients With Chronic Graft-Versus-Host Disease

NCT02759731Phase 1Completed

Study of Baricitinib, a JAK1/2 Inhibitor, in Chronic Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation

NCT02991846CompletedPrimary

A Prospective Observational Study for Evaluating CGVHD

NCT01903473Phase 2TerminatedPrimary

Donor Regulatory T Cells Infusion in Patients With Chronic Graft-versus-host Disease (GVHD)

NCT02966301Phase 2CompletedPrimary

Treatment of Chronic Graft Versus Host Disease With Arsenic Trioxide

NCT04692376Phase 2UnknownPrimary

MSC for Treatment of cGVHD After Allo-HSCT

NCT01898377Phase 2TerminatedPrimary

Imatinib Mesylate and Mycophenolate Mofetil for Steroid-Refractory Sclerotic/Fibrotic cGVHD in Children

NCT02918188Phase 2RecruitingPrimary

Therapeutic Effects of Hydrogen on Steroid-refractory/or Steroid-dependent cGVHD

NCT01862965Phase 2CompletedPrimary

Treatment of Newly Diagnosed Moderate or Severe Chronic Graft-versus-host Disease With Prednisone and Everolimus

NCT02040623Phase 2CompletedPrimary

Safety and Efficacy Study of R932348 Ophthalmic Solution in Chronic Ocular Graft Versus Host Disease Patients(DROPS-2)

NCT01161628Phase 2CompletedPrimary

Rituximab for the Primary Treatment of Denovo Extensive Chronic Graft Versus Host Disease (GVHD)

NCT01158105Phase 2UnknownPrimary

Bortezomib for the Treatment of Refractory Chronic Graft-vs-Host Disease(cGVHD)

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