Key Insights

Highlights

Success Rate

93% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

3.7%

1 terminated out of 27 trials

Success Rate

92.9%

+6.4% vs benchmark

Late-Stage Pipeline

11%

3 trials in Phase 3/4

Results Transparency

38%

5 of 13 completed with results

Key Signals

5 with results93% success

Data Visualizations

Phase Distribution

19Total
Not Applicable (5)
P 1 (7)
P 2 (4)
P 3 (3)

Trial Status

Completed13
Recruiting9
Active Not Recruiting2
Unknown1
Not Yet Recruiting1
Terminated1

Trial Success Rate

92.9%

Benchmark: 86.5%

Based on 13 completed trials

Clinical Trials (27)

Showing 20 of 20 trials
NCT02012699Recruiting

Integrated Cancer Repository for Cancer Research

NCT05511714UnknownPrimary

Expanded Access [11C] Methionine PET Imaging

NCT04185038Phase 1RecruitingPrimary

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

NCT04732065Phase 1Recruiting

ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

NCT06104488Phase 1Recruiting

A Study of Avutometinib for People With Solid Tumor Cancers

NCT07378683Not ApplicableRecruiting

A Clinical Prediction Model for Surgical Site Infection After Central Nervous System Tumor Surgery

NCT04852354RecruitingPrimary

Tissue Collection for Drug Screening and Bioanalysis

NCT06054295Recruiting

Somatic Mosaicism in Twins Discordant for Childhood Cancer

NCT02932280Phase 1Active Not Recruiting

Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment

NCT03452774Recruiting

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

NCT05978557RecruitingPrimary

Brain Slice Explants to Predict Drug Response in Brain Tumors

NCT04743310Phase 2CompletedPrimary

Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System

NCT03496402Not ApplicableActive Not Recruiting

Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults (MICCHADO)

NCT01595126CompletedPrimary

Longitudinal Study of Biomarkers

NCT03052738CompletedPrimary

Medical Marijuana in the Pediatric Central Nervous System Tumor Population

NCT06363201Not ApplicableNot Yet Recruiting

Effect and Safety of Ocoxin Oral Solution on the Quality of Life of Paediatric Patients With Advanced Stage Solid Tumours

NCT04096716Phase 1Terminated

Mapping Draining Lymph Nodes in CNS Malignancies

NCT00716976Phase 3Completed

Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy

NCT03981016Not ApplicableCompletedPrimary

Medical and Surgical Management of Patients With Brain Metastases

NCT02496520Phase 1Completed

Dendritic Cell-based Immunotherapy for Advanced Solid Tumours of Children and Young Adults

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