Central Nervous System Neoplasms
26
3
3
13
Key Insights
Highlights
Success Rate
68% trial completion
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 87/100
23.1%
6 terminated out of 26 trials
68.4%
-18.1% vs benchmark
0%
0 trials in Phase 3/4
23%
3 of 13 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 13 completed trials
Clinical Trials (26)
Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors
Pediatric Prospective Personalized Immune and Target Identification Trial
B7-H3.CD28Z.CART in CNS Neoplasms
Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
Neurobehavioral Functioning in Pediatric Brain Tumor Patients After Proton Beam Radiation Treatment
Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab
A Trial Using Velcade Plus Chemoradiation for Central Nervous System, Head and Neck, and Cervical Cancer Patients
EPO906 Plus Radiation Therapy for the Treatment of Cancer Patients
RRx-001 Given With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Solid and Central Nervous System Tumors
SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors
A Study of Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors
Diagnostic Assessment of 18F-fluciclovine and 18F-FDG -PET/MRI of Primary Central Nervous System Lymphoma
Mapping Draining Lymph Nodes in CNS Malignancies
Comparison of Contrast Agents for MRI Perfusion Analysis in Brain Tumor Patients
5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas
Diagnostic Efficiency of Artificial Intelligence for Surgical Neuropathology
Evaluation of Safety and Efficacy of ProHance in Pediatric Patients <2yrs
Biomarker Analysis of Central Nervous System Tumors
Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma