Key Insights

Highlights

Success Rate

68% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 87/100

Termination Rate

23.1%

6 terminated out of 26 trials

Success Rate

68.4%

-18.1% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

23%

3 of 13 completed with results

Key Signals

3 with results68% success

Data Visualizations

Phase Distribution

17Total
Not Applicable (3)
P 1 (12)
P 2 (2)

Trial Status

Completed13
Terminated6
Recruiting3
Not Yet Recruiting2
Unknown2

Trial Success Rate

68.4%

Benchmark: 86.5%

Based on 13 completed trials

Clinical Trials (26)

Showing 20 of 20 trials
NCT05835687Phase 1RecruitingPrimary

Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors

NCT04859543Not ApplicableCompletedPrimary

Pediatric Prospective Personalized Immune and Target Identification Trial

NCT07390539Phase 1Not Yet RecruitingPrimary

B7-H3.CD28Z.CART in CNS Neoplasms

NCT05386108Phase 1Recruiting

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

NCT04541082Phase 1RecruitingPrimary

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

NCT01180881Completed

Neurobehavioral Functioning in Pediatric Brain Tumor Patients After Proton Beam Radiation Treatment

NCT01931098Phase 2Completed

Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab

NCT00329589Phase 1Completed

A Trial Using Velcade Plus Chemoradiation for Central Nervous System, Head and Neck, and Cervical Cancer Patients

NCT00328458Phase 1CompletedPrimary

EPO906 Plus Radiation Therapy for the Treatment of Cancer Patients

NCT04525014Phase 1Terminated

RRx-001 Given With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Solid and Central Nervous System Tumors

NCT03434262Phase 1Completed

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

NCT03257631Phase 2CompletedPrimary

A Study of Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors

NCT03188354Not ApplicableCompleted

Diagnostic Assessment of 18F-fluciclovine and 18F-FDG -PET/MRI of Primary Central Nervous System Lymphoma

NCT04096716Phase 1TerminatedPrimary

Mapping Draining Lymph Nodes in CNS Malignancies

NCT02095353TerminatedPrimary

Comparison of Contrast Agents for MRI Perfusion Analysis in Brain Tumor Patients

NCT05850377Not Yet Recruiting

5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas

NCT04671368Not ApplicableUnknownPrimary

Diagnostic Efficiency of Artificial Intelligence for Surgical Neuropathology

NCT03750188Completed

Evaluation of Safety and Efficacy of ProHance in Pediatric Patients <2yrs

NCT02692898TerminatedPrimary

Biomarker Analysis of Central Nervous System Tumors

NCT01582152Phase 1Terminated

Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma

Scroll to load more

Research Network

Activity Timeline