Key Insights

Highlights

Success Rate

100% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

0.0%

0 terminated out of 26 trials

Success Rate

100.0%

+13.5% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

13%

1 of 8 completed with results

Key Signals

1 with results100% success

Data Visualizations

Phase Distribution

8Total
Not Applicable (3)
P 2 (5)

Trial Status

Recruiting11
Completed8
Unknown2
Active Not Recruiting2
Enrolling By Invitation1
Withdrawn1

Trial Success Rate

100.0%

Benchmark: 86.5%

Based on 8 completed trials

Clinical Trials (26)

Showing 20 of 20 trials
NCT07497867RecruitingPrimary

Long-term Prospective Study of Korean CADASIL Patients

NCT05491980Active Not Recruiting

Florida Cerebrovascular Disease Biorepository and Genomics Center

NCT02071784CompletedPrimary

Imaging Study of Neurovascular Coupling in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL)

NCT06935578RecruitingPrimary

RAre, But Not aLone: a Large Italian Network to Empower the Impervious diaGNostic Pathway of Rare cerEbrovascular Diseases (ALIGNED)

NCT04658823Phase 2CompletedPrimary

Efficacy and Safety of Tocotrienols in CADASIL

NCT05473637Recruiting

Taiwan Associated Genetic and Nongenetic Small Vessel Disease

NCT05677880RecruitingPrimary

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study

NCT02699190Completed

LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies

NCT03047369Recruiting

The Myelin Disorders Biorepository Project

NCT02795052Not ApplicableRecruiting

Neurologic Stem Cell Treatment Study

NCT02032225CompletedPrimary

Generation of a Cellular Model of CADASIL From Skin Fibroblasts

NCT06938100RecruitingPrimary

Genotype, Clinical Features and Imaging of Neuroradiological Abnormalities in CADASIL

NCT06859658Not Yet RecruitingPrimary

Development and Validation of a Functional MRI Biomarker of Cerebral Small Vessel Dysfunction in CADASIL

NCT05755997Phase 2Active Not RecruitingPrimary

CERebrolysin In CADASIL

NCT06148051RecruitingPrimary

AusCADASIL: An Australian Cohort of CADASIL

NCT03724136Not ApplicableEnrolling By Invitation

Alzheimer's Autism and Cognitive Impairment Stem Cell Treatment Study

NCT06072118Phase 2CompletedPrimary

Adrenomedullin for CADASIL

NCT04310098RecruitingPrimary

CADASIL Registry Study

NCT05902039RecruitingPrimary

MRI Study of Blood-brain Barrier Function in CADASIL

NCT05734378Recruiting

Prognosis of Cerebral Small Vessel Disease

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