Key Insights

Highlights

Success Rate

80% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

9.4%

11 terminated out of 117 trials

Success Rate

80.4%

-6.1% vs benchmark

Late-Stage Pipeline

6%

7 trials in Phase 3/4

Results Transparency

9%

4 of 45 completed with results

Key Signals

4 with results80% success11 terminated

Data Visualizations

Phase Distribution

64Total
Not Applicable (32)
Early P 1 (2)
P 1 (11)
P 2 (12)
P 3 (4)
P 4 (3)

Trial Status

Completed45
Unknown34
Recruiting13
Terminated11
Withdrawn8
Not Yet Recruiting3

Trial Success Rate

80.4%

Benchmark: 86.5%

Based on 45 completed trials

Clinical Trials (117)

Showing 20 of 20 trials
NCT04447833Phase 1CompletedPrimary

Mesenchymal Stromal Cell Therapy For The Treatment Of Acute Respiratory Distress Syndrome

NCT06119516Not ApplicableRecruitingPrimary

Transpulmonary Pressure - Guided Mechanical Ventilation in Morbidly Obese ARDS Patients: a Feasibility Study.

NCT05337059Not ApplicableCompletedPrimary

Feasabilty and Physiological Effects of a Ventilation Strategy Combining PEEP and Tidal Volume Titration According to Inspiratory and Expiratory Transpulmonary Pressures in ARDS Patients.

NCT04725110Phase 2Withdrawn

Direct Topical Lung T3 Treatment to Improve Outcome & Sequelae of COVID-19 Acute Respiratory Distress Syndrome

NCT05307913Not ApplicableCompletedPrimary

PET - PEEP by EIT for Acute Respiratory Distress Syndrome Trial

NCT05491681Phase 1WithdrawnPrimary

AllogeneiC Expanded Human MSC Therapy in Patients Recovering From COVID-19 Acute Respiratory Distress Trial

NCT03202641Not ApplicableTerminatedPrimary

Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients

NCT05492344Not ApplicableRecruitingPrimary

Personalized Mechanical Ventilation Guided by UltraSound in Patients With Acute Respiratory Distress Syndrome

NCT04356443Terminated

Non-Invasive Monitoring of Respiratory Function in Spontaneously Breathing Patients With COVID-19 Infection

NCT04115514Phase 2RecruitingPrimary

Treatment of ARDS With Instilled T3

NCT06444750Not Yet Recruiting

Comparison of the Proteome in ICU Patients in Search for TRALI Biomarkers: A Case-control Study Using Both Retrospective and Prospective Samples

NCT04751643Not ApplicableCompleted

Therapeutic Plasma Exchange to Alleviate Hyperinflammatory Condition During Severe Covid-19 Infections

NCT06164639Enrolling By InvitationPrimary

Potential Biomarkers and Pathogenic Mechanism for Reflux Aspiration-induced Lung Injury.

NCT07070362Recruiting

Digital Early Warning System for Acute Lung Injury in Liver Surgery

NCT03215316CompletedPrimary

Screening Expiratory Flow Limitation by Flow-time Curve

NCT03859050Not ApplicableRecruitingPrimary

Alveolar Macrophage Programming Following Endotoxin Exposure

NCT06250348CompletedPrimary

Exhaled Nitric Oxide : Biomarker of Acute Respiratory Distress Syndrome

NCT05795257RecruitingPrimary

Pulmonary Immune Cell-microbiome Interactions in ARDS

NCT04441047Phase 1Completed

Universal Anti-Viral Vaccine for Healthy Elderly Adults

NCT05847634RecruitingPrimary

Depth of Sedation and Its Impact on Cerebrovascular Reactivity in Acute Respiratory Distress Syndrome: a Pilot Analysis

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Research Network

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