Key Insights

Highlights

Success Rate

69% trial completion

Published Results

11 trials with published results (33%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

15.2%

5 terminated out of 33 trials

Success Rate

68.8%

-17.8% vs benchmark

Late-Stage Pipeline

3%

1 trials in Phase 3/4

Results Transparency

100%

11 of 11 completed with results

Key Signals

11 with results69% success

Data Visualizations

Phase Distribution

29Total
Not Applicable (1)
Early P 1 (1)
P 1 (10)
P 2 (16)
P 3 (1)

Trial Status

Completed11
Recruiting5
Terminated5
Active Not Recruiting4
Unknown4
Not Yet Recruiting3

Trial Success Rate

68.8%

Benchmark: 86.5%

Based on 11 completed trials

Clinical Trials (33)

Showing 20 of 20 trials
NCT07470489Phase 2Not Yet RecruitingPrimary

Zanzalintinib Plus Cemiplimab for the Treatment of BRAF Wild-Type Anaplastic Thyroid Cancer

NCT07485569Phase 1Not Yet Recruiting

Drug Repurposing in Thyroid Carcinoma: a Feasibility Trial

NCT05696548Phase 2Active Not RecruitingPrimary

Nivolumab Plus Lenvatinib Against Anaplastic Thyroid Cancer (NAVIGATION)

NCT06902376Phase 1RecruitingPrimary

XL092 and Cemiplimab in BRAF WT Thyroid Cancer

NCT06374602Phase 2RecruitingPrimary

Efficacy of Pembrolizumab and Lenvatinib in Patients With Anaplastic Thyroid Cancer

NCT03085056Early Phase 1Active Not RecruitingPrimary

Trametinib in Combination With Paclitaxel in the Treatment of Anaplastic Thyroid Cancer

NCT04238624Phase 2Active Not RecruitingPrimary

Study of Cemiplimab Combined With Dabrafenib and Trametinib in People With Anaplastic Thyroid Cancer

NCT04400474Phase 2Completed

Trial of Cabozantinib Plus Atezolizumab in Advanced and Progressive Neoplasms of the Endocrine System. The CABATEN Study

NCT04552769Phase 2Completed

Abemaciclib in Metastatic or Locally Advanced Anaplastic/Undifferentiated Thyroid Cancer

NCT04579757Phase 1Terminated

Surufatinib in Combination With Tislelizumab in Subjects With Advanced Solid Tumors

NCT04420754Phase 1Active Not RecruitingPrimary

Study of AIC100 CAR T Cells in Relapsed/Refractory Thyroid Cancer

NCT02152137Phase 2CompletedPrimary

Inolitazone Dihydrochloride and Paclitaxel in Treating Patients With Advanced Anaplastic Thyroid Cancer

NCT06235216Phase 2Recruiting

Sacituzumab govitEcan in THYroid Cancers

NCT06362694Phase 2RecruitingPrimary

Study of the Rechallenge Concept in Patients With BRAF-positive Anaplastic Thyroid Cancer After Progression on Anti-BRAF Therapy

NCT02244463Phase 1CompletedPrimary

A Phase I/II Study of MLN0128 in Metastatic Anaplastic Thyroid Cancer and Incurably Poorly Differentiated or Radioidodine Refractory Differentiated Thyroid Cancer

NCT06079333Phase 2RecruitingPrimary

NEO- and Adjuvant Targeted Therapy in Braf-mutated Anaplastic Cancer of the Thyroid (NEO-ATACT Study)

NCT05102292Phase 1UnknownPrimary

The Efficacy and Safety of HLX208 in Advanced Anaplastic Thyroid Cancer (ATC) With BRAF V600 Mutation

NCT05819593Not Yet RecruitingPrimary

Evaluating Trends in Anaplastic Thyroid Cancer Patients' Clinical Study Experiences

NCT05796960Unknown

European Multicenter Study on Surgical Management of Advanced Thyroid Cancer

NCT02404441Phase 1Completed

Phase I/II Study of PDR001 in Patients With Advanced Malignancies

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