Key Insights

Highlights

Success Rate

80% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

10.3%

3 terminated out of 29 trials

Success Rate

80.0%

-6.5% vs benchmark

Late-Stage Pipeline

10%

3 trials in Phase 3/4

Results Transparency

50%

6 of 12 completed with results

Key Signals

6 with results80% success

Data Visualizations

Phase Distribution

17Total
Not Applicable (2)
P 1 (2)
P 2 (10)
P 3 (1)
P 4 (2)

Trial Status

Completed12
Recruiting8
Terminated3
Active Not Recruiting3
Not Yet Recruiting2
Unknown1

Trial Success Rate

80.0%

Benchmark: 86.5%

Based on 12 completed trials

Clinical Trials (29)

Showing 20 of 20 trials
NCT04571658Not ApplicableRecruiting

NEPTUNE Match Study

NCT06499948Phase 4Active Not RecruitingPrimary

Albuminuria Lowering Effect of Dapagliflozin, Spironolactone and Their Combination in Adult Patients With Alport Syndrome (COMBINE-ALPORT)

NCT06526741RecruitingPrimary

ASF Alport Patient Registry

NCT06274489Phase 1CompletedPrimary

A Study to Evaluate Setanaxib in Patients With Alport Syndrome

NCT07211685Phase 2RecruitingPrimary

BAY3401016; Biomarker Study Alport

NCT05448755Phase 2CompletedPrimary

A Study of ELX-02 in Patients With Alport Syndrome

NCT06425055Phase 2CompletedPrimary

Vonafexor ALPort Syndrome Efficacy & Safety TRIAl-1 (ALPESTRIA-1)

NCT05003986Phase 2Recruiting

Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

NCT00481130CompletedPrimary

Alport Syndrome Treatments and Outcomes Registry

NCT05267262Phase 2CompletedPrimary

Study to Evaluate R3R01 in Patients With Alport Syndrome and Patients With Focal Segmental Glomerulosclerosis

NCT05927467RecruitingPrimary

Eurbio-Alport (RaDiCo Cohort) (RaDiCo Eurbio-Alport)

NCT02855268Phase 2TerminatedPrimary

Study of Lademirsen (SAR339375) in Patients With Alport Syndrome

NCT05687474Completed

Baby Detect : Genomic Newborn Screening

NCT04573920Phase 2Active Not Recruiting

Atrasentan in Patients With Proteinuric Glomerular Diseases

NCT03019185Phase 2CompletedPrimary

A Phase 2/3 Trial of the Efficacy and Safety of Bardoxolone Methyl in Patients With Alport Syndrome - CARDINAL

NCT03749447Phase 3Terminated

An Extended Access Program for Bardoxolone Methyl in Patients With CKD (EAGLE)

NCT02378805RecruitingPrimary

Alport Therapy Registry - European Initiative Towards Delaying Renal Failure in Alport Syndrome

NCT06731192Phase 2Not Yet RecruitingPrimary

Human Umbilical Cord Mesenchymal Stem Cells for Alport Syndrome

NCT06226896Active Not RecruitingPrimary

Effects of Dapagliflozin on Progression of Alport Syndrome

NCT06065852Recruiting

National Registry of Rare Kidney Diseases

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