Key Insights

Highlights

Success Rate

81% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

10.0%

3 terminated out of 30 trials

Success Rate

81.3%

-5.3% vs benchmark

Late-Stage Pipeline

10%

3 trials in Phase 3/4

Results Transparency

46%

6 of 13 completed with results

Key Signals

6 with results81% success

Data Visualizations

Phase Distribution

17Total
Not Applicable (2)
P 1 (2)
P 2 (10)
P 3 (1)
P 4 (2)

Trial Status

Completed13
Recruiting9
Terminated3
Active Not Recruiting2
Not Yet Recruiting2
Unknown1

Trial Success Rate

81.3%

Benchmark: 86.6%

Based on 13 completed trials

Clinical Trials (30)

Showing 20 of 20 trials
NCT07211685Phase 2RecruitingPrimary

A Study to Learn About How Well BAY 3401016 Works in Adults With Alport Syndrome

NCT07575347Recruiting

Periodontal Disease in Rare Renal Disorders (PERIO-RA-RE)

NCT06499948Phase 4CompletedPrimary

Albuminuria Lowering Effect of Dapagliflozin, Spironolactone and Their Combination in Adult Patients With Alport Syndrome (COMBINE-ALPORT)

NCT04571658Not ApplicableRecruiting

NEPTUNE Match Study

NCT04573920Phase 2Active Not Recruiting

Atrasentan in Patients With Proteinuric Glomerular Diseases

NCT05003986Phase 2Recruiting

Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

NCT06526741RecruitingPrimary

ASF Alport Patient Registry

NCT06274489Phase 1CompletedPrimary

A Study to Evaluate Setanaxib in Patients With Alport Syndrome

NCT05448755Phase 2CompletedPrimary

A Study of ELX-02 in Patients With Alport Syndrome

NCT06425055Phase 2CompletedPrimary

Vonafexor ALPort Syndrome Efficacy & Safety TRIAl-1 (ALPESTRIA-1)

NCT00481130CompletedPrimary

Alport Syndrome Treatments and Outcomes Registry

NCT05267262Phase 2CompletedPrimary

Study to Evaluate R3R01 in Patients With Alport Syndrome and Patients With Focal Segmental Glomerulosclerosis

NCT05927467RecruitingPrimary

Eurbio-Alport (RaDiCo Cohort) (RaDiCo Eurbio-Alport)

NCT02855268Phase 2TerminatedPrimary

Study of Lademirsen (SAR339375) in Patients With Alport Syndrome

NCT05687474Completed

Baby Detect : Genomic Newborn Screening

NCT03019185Phase 2CompletedPrimary

A Phase 2/3 Trial of the Efficacy and Safety of Bardoxolone Methyl in Patients With Alport Syndrome - CARDINAL

NCT03749447Phase 3Terminated

An Extended Access Program for Bardoxolone Methyl in Patients With CKD (EAGLE)

NCT02378805RecruitingPrimary

Alport Therapy Registry - European Initiative Towards Delaying Renal Failure in Alport Syndrome

NCT06731192Phase 2Not Yet RecruitingPrimary

Human Umbilical Cord Mesenchymal Stem Cells for Alport Syndrome

NCT06226896Active Not RecruitingPrimary

Effects of Dapagliflozin on Progression of Alport Syndrome

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