Key Insights

Highlights

Success Rate

88% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

7.7%

1 terminated out of 13 trials

Success Rate

87.5%

+1.0% vs benchmark

Late-Stage Pipeline

8%

1 trials in Phase 3/4

Results Transparency

29%

2 of 7 completed with results

Key Signals

2 with results88% success

Data Visualizations

Phase Distribution

10Total
Not Applicable (3)
P 1 (1)
P 2 (5)
P 3 (1)

Trial Status

Completed7
Recruiting3
Withdrawn2
Terminated1

Trial Success Rate

87.5%

Benchmark: 86.5%

Based on 7 completed trials

Clinical Trials (13)

Showing 13 of 13 trials
NCT02699190Completed

LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies

NCT03047369Recruiting

The Myelin Disorders Biorepository Project

NCT04925349Recruiting

Modeling Macrophages Activation Pattern in X-linked Adrenoleukodystrophy, Metachromatic Leukodystrophy and Adult Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia

NCT05443906Not ApplicableRecruiting

Home Exercise for Individuals with Neurodegenerative Disease

NCT05146284Phase 2WithdrawnPrimary

Study to Assess PXL770 in Subjects With Adrenomyeloneuropathy (AMN) Form of X-linked Adrenoleukodystrophy (X-ALD or ALD)

NCT04303416Phase 2CompletedPrimary

Plasma Exchange With Albumin in AMN Patients

NCT03627416Not ApplicableCompleted

Repetitive Transcranial Magnetic Stimulation as Therapy in Hereditary Spastic Paraplegia and Adrenomyeloneuropathy

NCT03864523Phase 2CompletedPrimary

Effect of Pioglitazone Administered to Patients With Adrenomyeloneuropathy

NCT01495260Phase 2CompletedPrimary

A Clinical Trial for AMN: Validation of Biomarkers of Oxidative Stress, Efficacy and Safety of a Mixture of Antioxidants

NCT02961803Phase 2CompletedPrimary

MD1003-AMN MD1003 in Adrenomyeloneuropathy

NCT01787578Phase 1Withdrawn

Safety and Pharmacodynamic Study of Sobetirome in X-Linked Adrenoleukodystrophy (X-ALD)

NCT00545597Phase 3TerminatedPrimary

A Phase III Trial of Lorenzo's Oil in Adrenomyeloneuropathy

NCT01165060Not ApplicableCompleted

The Effect of Bezafibrate on the Level of Very Long Chain Fatty Acids (VLCFA) in X-linked Adrenoleukodystrophy (X-ALD)

Showing all 13 trials

Research Network

Activity Timeline