Key Insights

Highlights

Success Rate

78% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

11.8%

2 terminated out of 17 trials

Success Rate

77.8%

-8.7% vs benchmark

Late-Stage Pipeline

12%

2 trials in Phase 3/4

Results Transparency

57%

4 of 7 completed with results

Key Signals

4 with results78% success

Data Visualizations

Phase Distribution

16Total
P 1 (11)
P 2 (3)
P 3 (2)

Trial Status

Completed7
Recruiting3
Terminated2
Unknown2
Withdrawn2
Active Not Recruiting1

Trial Success Rate

77.8%

Benchmark: 86.5%

Based on 7 completed trials

Clinical Trials (17)

Showing 17 of 17 trials
NCT05101213Phase 1RecruitingPrimary

Study Assessing the Feasibility, Safety and Efficacy of Genetically Engineered Glucocorticoid Receptor Knock Out Virus Specific CTL Lines for Viral Infections in Immunosuppressed Cancer Patients

NCT07104591Unknown

TETRAVI Expanded Access Program

NCT04722029Phase 1RecruitingPrimary

Pilot Study of Haploidentical Donor Adenovirus Specific T-lymphocytes to Treat Refractory Adenovirus Infections

NCT03475212Phase 1Active Not Recruiting

Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation

NCT02007356Phase 2RecruitingPrimary

A Study to Assess Safety and Feasibility of Direct Infusions of Donor-derived Virus-specific T-cells in Recipients of Hematopoietic Stem Cell Transplantation With Post-transplant Viral Infections Using the Cytokine Capture System®

NCT05305040Phase 2TerminatedPrimary

Study of Posoleucel (ALVR105,Viralym-M) for Multi-Virus Prevention in Patients Post-Allogeneic Hematopoietic Cell Transplant

NCT04693637Phase 2CompletedPrimary

Posoleucel (ALVR105, Formerly Viralym-M) for Multi-Virus Prevention in Patients Post-Allogeneic Hematopoietic Cell Transplant

NCT05179057Phase 3TerminatedPrimary

Posoleucel (ALVR105) for the Treatment of Adenovirus Infection in Pediatric and Adult Participants Receiving Standard of Care Following Allogeneic Hematopoietic Cell Transplantation

NCT02087306Phase 3CompletedPrimary

Study to Assess the Safety and Efficacy of Brincidofovir in Treatment of Early Versus Late Adenovirus Infection

NCT03159364Phase 1Unknown

Antigen-specific Cytotoxic T Cells in the Treatment of Opportunistic Infections

NCT02702427Phase 1Withdrawn

Virus-specific ImmunoTherapy Following Allogeneic Stem Cell Transplantation

NCT02276820Phase 1WithdrawnPrimary

Most Closely Human Leukocyte Antigen (HLA)-Matched Adenovirus-specific T Lymphocytes (Viralym-A)

NCT02851576Phase 1CompletedPrimary

Clinical Grade Adenovirus Specific T Cells for Immunotherapy After Allogeneic Stem Cell Transplantation (CTL-ADV)

NCT00711035Phase 1CompletedPrimary

Most Closely HLA Matched Allogeneic Virus Specific Cytotoxic T-Lymphocytes (CTL)

NCT00880789Phase 1Completed

Safety, Toxicity and MTD of One Intravenous IV Injection of Donor CTLs Specific for CMV and Adenovirus

NCT01070797Phase 1CompletedPrimary

Administration of Rapidly Generated Multivirus-specific Cytotoxic T-Lymphocytes (VIRAGE)

NCT00590083Phase 1CompletedPrimary

Administration of Virus-Specific Cytotoxic T-Lymphocytes

Showing all 17 trials

Research Network

Activity Timeline