Key Insights

Highlights

Success Rate

82% trial completion

Published Results

28 trials with published results (24%)

Research Maturity

61 completed trials (52% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

11.1%

13 terminated out of 117 trials

Success Rate

82.4%

-4.1% vs benchmark

Late-Stage Pipeline

3%

4 trials in Phase 3/4

Results Transparency

46%

28 of 61 completed with results

Key Signals

28 with results82% success13 terminated

Data Visualizations

Phase Distribution

108Total
Not Applicable (9)
P 1 (64)
P 2 (31)
P 3 (4)

Trial Status

Completed61
Unknown17
Terminated13
Recruiting13
Withdrawn6
Active Not Recruiting6

Trial Success Rate

82.4%

Benchmark: 86.5%

Based on 61 completed trials

Clinical Trials (117)

Showing 20 of 20 trials
NCT04771572Phase 1Recruiting

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

NCT06476665Active Not RecruitingPrimary

A Study to Learn About the Safety of BESPONSA Injection in Pediatric Patients With Acute Lymphocytic Leukemia.

NCT02315612Phase 1Completed

Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults With Recurrent or Refractory CD22-expressing B Cell Malignancies

NCT03633955Phase 1RecruitingPrimary

Pilot Imaging Study of Leukemia

NCT03934372Phase 1Recruiting

Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors

NCT05456698Phase 2Active Not RecruitingPrimary

Efficacy and Safety of Inotuzumab Ozogamicin in Treating Adult Patients With Ph Negative ALL With Minimal Residual Disease Positive After Induction Chemotherapy

NCT01890486Recruiting

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

NCT06481735Phase 1RecruitingPrimary

TCR Reserved and Power3 (SPPL3) Gene Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B-ALL

NCT05442515Phase 1Recruiting

CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies

NCT06904482Phase 2Recruiting

Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood

NCT05170828Phase 1Withdrawn

Cryopreserved MMUD BM With PTCy for Hematologic Malignancies

NCT06131801Recruiting

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

NCT00586391Phase 1Active Not Recruiting

CD19 Chimeric Receptor Expressing T Lymphocytes In B-Cell Non Hodgkin's Lymphoma, ALL & CLL

NCT05044039Phase 1Active Not Recruiting

Duvelisib Following Chimeric Antigen Receptor T-Cell Therapy

NCT07371533Not ApplicableNot Yet RecruitingPrimary

Clinical Study of Recombinant Anti-CD19m-CD3 Antibody Injection (A-319)

NCT03674411Phase 2Active Not Recruiting

Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy

NCT01853631Phase 1Recruiting

Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN)

NCT05923112CompletedPrimary

BESPONSA Injection 1 mg Special Investigation

NCT05805605Phase 2Recruiting

Allo HSCT Using RIC and PTCy for Hematological Diseases

NCT07008885Phase 1RecruitingPrimary

BCOR and ZC3H12 Genes Knock-out CD19-targeting CAR-T Cell Therapy in r/r B-ALL

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