Trials Sponsors Conditions Drugs Pricing

Conditions

Post-inflammatory Hyperpigmentation Post-acne Hyperpigmentation

Keywords

Post-Inflammatory Hyperpigmentationpost-acne hyperpigmentationacnehyperpigmentationskin of colorFST

Outcome Measures

Primary Outcomes (1)

Change from baseline in PIH of the face at Week 12, as assessed by the Post-Acne Hyperpigmentation Index (PAHPI) score
Total scores on the PAHPI range from 6 to 22, with higher scores indicating greater severity of post-acne hyperpigmentation
Baseline; 12 weeks

Secondary Outcomes (2)

Number or participants who tolerated the investigational product as assessed by the investigator
Up to 12 weeks
Patient-reported stigmatization, as measured by the PUSH-D questionnaire at week 12
Baseline; Week 12

Study Arms (1)

Participants with Acne-Associated Post-Inflammatory Hyperpigmentation using the Vinoperfect Serum

OTHER

Participants will undergo a standardized twice-daily skincare regimen for 12 weeks. In the morning, participants will cleanse their face, apply the Vinoperfect Brightening Serum, apply moisturizer, and then apply SPF 50+ sunscreen. In the evening, participants will cleanse their face, apply the Vinoperfect Brightening Serum, and apply moisturizer.

Other: Vinoperfect brightening serum

Interventions

Vinoperfect brightening serumOther

Participants with Acne-Associated Post-Inflammatory Hyperpigmentation using the Vinoperfect Serum

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Male or female participants aged ≥18 years.
Participants with Fitzpatrick Skin Types IV, V, or VI.

Sponsors & Collaborators

Caudalie
Industrycollaborator
Weill Medical College of Cornell University
Otherlead

Study Sites (1)

Weill Cornell Medicine Dermatology

New York, New York, 10022, United States

Angelica Nazarian, MDCONTACT6469622090 dermres@med.cornell.edu

Olumayowa Adebiyi, MD, MHSCONTACT6469626054 dermres@med.cornell.edu

Andrew Alexis, MD, MPHPRINCIPAL INVESTIGATOR

Angelica Nazarian, MDSUB INVESTIGATOR

Olumayowa Adebiyi, MD, MHSSUB INVESTIGATOR

MeSH Terms

Conditions

HyperpigmentationAcne Vulgaris

Condition Hierarchy (Ancestors)

Pigmentation DisordersSkin DiseasesSkin and Connective Tissue DiseasesAcneiform EruptionsSebaceous Gland Diseases

Study Officials

Andrew Alexis, MD, MPH
Weill Medical College of Cornell University
PRINCIPAL INVESTIGATOR

Central Study Contacts

Andrew Alexis, MD, MPH

CONTACT

6469623376 dermres@med.cornell.edu

Angelica Nazarian, MD

CONTACT

6469622090

Study Design

Study Type: interventional
Phase: not applicable
Allocation: NA
Masking: NONE
Purpose: TREATMENT
Intervention Model: SINGLE GROUP
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

October 20, 2026

First Posted

October 27, 2026

Study Start

September 2026

Estimated (date passed)

This estimate has passed. The registry has not confirmed an actual date for this milestone.

Primary Completion

January 15, 2027

Estimated

A Single-Center, Open-Label Study to Assess the Efficacy and Tolerability of a Brightening Serum in Skin of Color Patients With Post Inflammatory Hyperpigmentation

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (2)

Study Arms (1)

Participants with Acne-Associated Post-Inflammatory Hyperpigmentation using the Vinoperfect Serum

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (2)

Study Arms (1)

Participants with Acne-Associated Post-Inflammatory Hyperpigmentation using the Vinoperfect Serum

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations