Sponsor study identifier
observational
120
1 country
1
Study Start
January 2014
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2017
Actual (reported)Study Completion
December 2017
Actual (reported)In recent years, evaluating cardiac function with magnetic resonance imaging (MRI) has drawn widespread interest. However, cardiac MRI is prone to severe motion artifacts from cardiac contraction, frequently requiring complex triggering procedures to enhance image quality-a task that typically demands a highly skilled technologist to execute within limited clinical time. As there is currently no optimized cardiac MRI protocol at Chang Gung Memorial Hospital, this subproject aims to first establish a clinically feasible, optimized protocol to support other subprojects and future studies. The investigators will develop a standard operating procedure (SOP) and subsequently use it to evaluate recovery in heart failure patients. Over this three-year project, the investigators plan to use MRI to evaluate cardiac morphology and function in heart failure patients. In Year 1, the investigators will establish a clinically feasible protocol to assess myocardial stability; baseline images from healthy controls will be incorporated into the integrated project. In Year 2, the investigators will introduce accelerated imaging techniques, assess the correlation between disease severity and MRI findings, and measure cardiac diffusion parameters. In Year 3, the investigators will follow heart failure patients to monitor their recovery process.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2017
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 2014
Date type not reportedThis date has not been verified as actual or estimated.
December 2017
Actual (reported)December 2017
Actual (reported)August 12, 2022
Actual (reported)October 22, 2026
Actual (reported)MRI acquisition
73 normal participants assesed by MRI
3 years
* Aged between 20 and 70 year old. * Able to understand and provide signed informed consent. * Without documented cardiac disorder. * Age and gender matched the heart failure group
* Aged between 20 and 70 year old. * Able to understand and provide signed informed consent * without documented cardiac disorder * Age and gender matched the heart failure group
* All participants should be aged between 20 and 70 year old. * Established diagnosis by a cardiological examination. * Able to understand and provide signed informed consent. * Patients must be willing to undergo standard treatment and follow up in the Heart Failure Center.
The healthy control will be recruited from the local community in northern Taiwan.
Keelung ChangGung Memorial Hospital
Keelung, Taiwan, 204, Taiwan
Jiun-Jie Wang, PhD
ChangGung University
120 participants (actual enrollment reported by the registry).
First Submitted
August 12, 2022
First Posted
October 22, 2026
Study Start
January 2014
Date type not reportedThis date has not been verified as actual or estimated.
Sildenafil Impact on Ventricular Function in Patients With Heart Failure
Contact the study team to confirm eligibility.
Primary Completion
December 2017
Actual (reported)Study Completion
December 2017
Actual (reported)Last Updated
October 22, 2026
Record last verified: 2026-10
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Source: ClinicalTrials.gov.
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