NCT07887425

Brief Summary

Tear fluid will be collected from patients diagnosed with ocular trauma at the University of Pittsburgh Medical Center to evaluate biomarkers.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
12mo left

Started Nov 2026

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 14, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

October 21, 2026

Completed
11 days until next milestone

Study Start

First participant enrolled

November 1, 2026

Expected
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2027

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2027

Last Updated

October 21, 2026

Status Verified

October 1, 2026

Enrollment Period

1 year

First QC Date

October 14, 2026

Last Update Submit

October 14, 2026

Conditions

Ocular Trauma

Outcome Measures

Primary Outcomes (1)

  • Primary Outcome - Ascorbic Acid

    Measurement of ascorbic acid using mass spec

    One year.

Study Arms (1)

Patients with ocular trauma

EXPERIMENTAL
Diagnostic Test: Tear fluid collection with mass spec analysis.

Interventions

Tear fluid collection with mass spec analysis.DIAGNOSTIC_TEST

Tear fluid collection with mass spec analysis.

Patients with ocular trauma

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Minimum age of 18 years.
  • Diagnosis of visually significant cataract and scheduled for routine cataract surgery at UPMC with a clear corneal incision or
  • scheduled for clinical repair of a full-thickness corneal laceration.

You may not qualify if:

  • Prior history of full-thickness corneal laceration from trauma or from a surgical procedure
  • Current diagnosis of glaucoma or use of ocular hypotensive drops or oral aqueous suppressants.
  • Actively being treated for the diagnosis of dry eyes with a topical drop other than artificial tears.
  • Actively taking oral or topical supplementation of Vitamin C.
  • Scheduled for additional eye surgeries, combined with the routine cataract surgery.
  • Surgical plan that would include incisions in the clear for cataract extraction.
  • Inability to provide informed consent due to suspected head trauma, altered mental status, or other factors impairing decision-making capacity.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UPMC Vision Insititute - Mercy Pavilion

Pittsburgh, Pennsylvania, 15219, United States

RECRUITING

Central Study Contacts

PI

CONTACT

866-202-4296info@innsightech.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 14, 2026

First Posted

October 21, 2026

Study Start (Estimated)

November 1, 2026

Primary Completion (Estimated)

November 1, 2027

Study Completion (Estimated)

November 1, 2027

Last Updated

October 21, 2026

Record last verified: 2026-10

Locations

US(1)