Color Stability of Darkly Discolored Arrested Caries Lesions Following Bleaching Treatment

NCT07886255 | Completed

• 1 other identifier: 2022/51
• Study Type: observational
• Target: 27
• Locations: 1 country
• Sites: 1

Brief Summary

This observational study evaluated the color stability of darkly discolored arrested caries lesions (DDACL) on anterior teeth following in-office bleaching with 40% hydrogen peroxide, in comparison with healthy teeth. Tooth color (spectrophotometer, CIELAB, CIEDE2000), laser fluorescence (DIAGNODent Pen), ICDAS II codes, and patient and clinician color satisfaction were assessed at baseline, immediately after bleaching, and at 1 week and 3 months.

Conditions

Dental Caries; Tooth Discoloration

Keywords

Arrested caries; Bleaching; Color stability; Laser fluorescence

Outcome Measures

Primary Outcomes (1)

• Color change (CIEDE2000 ΔE00) from baseline to 3 months after bleaching

  Tooth color was measured with a Vita Easyshade spectrophotometer (CIELAB L\*, a\*, b\*), and color differences were calculated with the CIEDE2000 formula (ΔE00) between baseline and each follow-up time point (immediately after bleaching, 1 week, and 3 months), separately for DDACL and healthy teeth.

  3 months

Secondary Outcomes (3)

• Change in laser fluorescence (DIAGNODent Pen) values from baseline to 3 months

  3 months

• Change in ICDAS II codes of DDACL teeth from baseline to 3 months

  3 months

• Change in participant and clinician color satisfaction score (1-10) from baseline to 3 months

  3 months

Study Arms (2)

DDACL group

Patients with darkly discolored arrested caries lesions (DDACL) on anterior teeth who underwent in-office bleaching with 40% hydrogen peroxide.

Healthy teeth group

Patients with healthy anterior teeth who underwent in-office bleaching with 40% hydrogen peroxide.

Eligibility Criteria

• Age: 18 Years - 55 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients (18-55 years) attending the Department of Restorative Dentistry, Faculty of Dentistry, Selçuk University, with darkly discolored arrested caries lesions on anterior teeth or with healthy anterior teeth, who were scheduled for in-office bleaching.

You may qualify if:

• Aged between 18 and 55 years
• No missing maxillary or mandibular anterior and premolar teeth
• No restorations, cavitations, or active caries on the facial surface of these teeth
• Able to attend regular follow-up appointments

You may not qualify if:

• Medically compromised patients
• History of previous bleaching treatment
• Poor oral hygiene
• Cavitated or active caries lesions or restorations on the facial surface of the target teeth

Sponsors & Collaborators

• Selcuk University: lead

Study Sites (1)

Selçuk University Faculty of Dentistry

Konya, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Dental Caries; Tooth Discoloration

Condition Hierarchy (Ancestors)

Tooth Demineralization; Tooth Diseases; Stomatognathic Diseases

Study Officials

• Merve Albakır Yiğit, DDS, Specialist

  Selçuk University Faculty of Dentistry

  PRINCIPAL INVESTIGATOR

• Nevin Çobanoğlu, Prof

  Selçuk University Faculty of Dentistry

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Specialist in Restorative Dentistry

Study Record Dates

• First Submitted: October 9, 2026
• First Posted: October 21, 2026
• Study Start: February 10, 2023
• Primary Completion: September 21, 2023
• Study Completion: September 21, 2023
• Last Updated: October 21, 2026

Record last verified: 2026-10

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)