Trials Sponsors Conditions Drugs Pricing

Conditions

AF - Atrial Fibrillation

Keywords

Symptomatic AFPersistent AF

Outcome Measures

Primary Outcomes (1)

Number of participants free of AF, AFl, or AT recurrence
AF/AFl/AT Recurrence
12 months

Secondary Outcomes (2)

Number of participants free of AF, AFl, or AT recurrence
36 months
Number of participants free of repeat ablation
12 months

Study Arms (2)

PFA System A

ACTIVE COMPARATOR

Pulse Field System A through a standard ablation catheter

Procedure: Pulse Field Ablation

PFA System B

ACTIVE COMPARATOR

Pulse Field System A through a standard ablation catheter

Procedure: Pulse Field Ablation

Interventions

Pulse Field AblationProcedure

Pulse Field Ablation

PFA System APFA System B

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years - 89 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Symptomatic AF
Persistent AF

Sponsors & Collaborators

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Otherlead

Study Sites (1)

Allegheny General Hospital

Pittsburgh, Pennsylvania, 15212, United States

RECRUITING

Heather McDonald, MHA, CCRCCONTACT412-359-3660 heather.mcdonald@ahn.org

Amit Thosani, MDPRINCIPAL INVESTIGATOR

MeSH Terms

Conditions

Atrial Fibrillation

Interventions

Irreversible Electroporation Therapy

Condition Hierarchy (Ancestors)

Arrhythmias, CardiacHeart DiseasesCardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Electroporation TherapiesTherapeuticsElectroporationCytological TechniquesClinical Laboratory Techniques

Study Officials

Amit Thosani, MD
Allegheny Health Network
PRINCIPAL INVESTIGATOR

Central Study Contacts

Amit Thosani, MD

CONTACT

412-359-3457 amit.thosani@ahn.org

Caitlin Phalunas, Lead CRC

CONTACT

412-359-3747

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: SINGLE
Who Masked: OUTCOMES ASSESSOR
Purpose: TREATMENT
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

April 27, 2026

First Posted

October 20, 2026

Study Start

July 10, 2026

Actual (reported)

Primary Completion

August 30, 2028

Comparison of Two Pulse Field Ablation Systems for AF Ablation

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

Study Start

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (2)

Study Arms (2)

PFA System A

PFA System B

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

Study Start

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (2)

Study Arms (2)

PFA System A

PFA System B

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations