NCT07883200|RecruitingDMC
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Sponsor study identifier
interventional
30
1 country
1
Study Start
November 25, 2025
Actual (reported)Primary Completion
November 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
December 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
This randomized controlled split-mouth clinical trial evaluates the clinical and radiographic performance of E-IodoCal paste compared to zinc oxide-eugenol (ZOE) as root canal filling materials in primary molar pulpectomies.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
November 25, 2025
Actual (reported)October 13, 2026
Actual (reported)October 20, 2026
Actual (reported)November 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
December 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Clinical Success Rate
Measure: Binary evaluation (Success/Failure) based on the complete absence of: Spontaneous or stimulated pain. Soft tissue swelling or draining sinus tract. Pathological tooth mobility. Tenderness to percussion / normal function on biting.
Evaluated at 3, 6, and 9 months post-operative.
Radiographic Success Rate
Measure: Binary evaluation (Success/Failure) assessed via standardized digital periapical radiographs based on: Complete absence or reduction in size of periapical/interradicular radiolucency. Absence of pathological root resorption (internal or external). Normal, uniform, and unwidened periodontal ligament space with an intact, unbroken lamina dura.
Evaluated at 3, 6, and 9 months post-operative.
Non-vital primary molars undergoing pulpectomy and obturated using pre-mixed E-IodoCal paste (calcium hydroxide, iodoform, and silicone oil).
Non-vital primary molars undergoing pulpectomy and obturated using conventional Zinc Oxide-Eugenol (ZOE) paste.
Chemo-mechanical preparation: Rubber dam isolation, access opening, pulp tissue removal, working length determination, manual instrumentation up to #30-#35 using 17% EDTA gel lubricant, and standard irrigation with 2.5% sodium hypochlorite and normal saline. Canals are dried with sterile paper points. Obturation: E-IodoCal paste delivered using its pre-packed polypropylene syringe inserted 1 mm short of the apex, withdrawing slowly as canals fill. Restoration: Intermediate glass ionomer base (Medifil) followed by a final stainless steel crown.
faculty of dentistry, Tanta university
Tanta, Egypt
Boutsiouki C, Frankenberger R, Kramer N. Clinical and radiographic success of (partial) pulpotomy and pulpectomy in primary teeth: A systematic review. Eur J Paediatr Dent. 2021 Dec;22(4):273-285. doi: 10.23804/ejpd.2021.22.04.4.
Reddy VV, Fernandes. Clinical and radiological evaluation of zinc oxide-eugenol and Maisto's paste as obturating materials in infected primary teeth--nine months study. J Indian Soc Pedod Prev Dent. 1996 Jun;14(2):39-44.
First Submitted
October 13, 2026
First Posted
October 20, 2026
Study Start
November 25, 2025
Actual (reported)Primary Completion
November 2026
EstimatedThe Effect of Prognostic Factors on the Success of Full Pulpotomy in Permanent Mature Molars With Irreversible Pulpitis
Overfill Clearance Rate
At 3 months, 6 months, and 9 months post-operative.
Intracanal Material Resorption Rate
At 3 months, 6 months, and 9 months post-operative
Preparation: Identical isolation, access, cleaning, shaping, and drying protocol as Group I. Obturation: ZOE paste carried into canals in small increments using a hand plugger rotated counterclockwise until complete obturation is achieved. Restoration: Identical glass ionomer base and final stainless steel crown placement.
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Planned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
December 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
October 22, 2026
Record last verified: 2026-10
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Source: ClinicalTrials.gov.
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