Trials Sponsors Conditions Drugs Pricing

Conditions

Spastic Diplegia Cerebral Palsy

Keywords

cerebral palsySpastic Diplegia Cerebral Palsyunderwater exerciseradial extracorporeal shock wave therapy

Outcome Measures

Primary Outcomes (1)

1- Modified Ashworth Scale (MAS)
The MAS measures the muscle group's resistance to passive stretching on a six-point ordinal scale that ranges from 0 (no increase in muscle tone) to 4. A score of 1 indicates a slight increase in muscle tone with a catch and release, whereas a score of 2 indicates a more notable increase in muscle tone across the range of motion. A score of 3 shows a significant increase in muscle tone; passive movement is complex, and there is a "catch" at a particular place in the range of motion. A score of 4 represents stiff flexion or extension.
12 weeks

Secondary Outcomes (2)

2- The Gross Motor Function Measure-66 (GMFM-66)
12 weeks
3- Pediatric Quality of Life Inventory (PedsQL)
12 weeks

Study Arms (2)

group A: underwater exercise

EXPERIMENTAL

Aquatic Neuromotor Repatterning Program (ANRP)

Other: Group A

group B: radial extracorporeal shock wave therapy.

EXPERIMENTAL

Targeted Neuromodulatory Shockwave Protocol (TNMSP)

Other: Group B

Interventions

Group AOther

Underwater exercise was conducted five times per week for 12 weeks. Each session took place for 60 minutes in a therapy pool with water temperatures between 33-35°С. The water depth ranged from chest deep to waist deep, depending on the functional level and progress of each participant. Sessions were structured into five parts. Each session began with 10 minutes of warm-up consisting of water walking with support, slow water marching, and body awareness exercises using aquatic foam noodles. After the warm-up, patients spent 15 minutes practicing neuromotor control in buoyancy. The goals of this portion were to reduce co-contraction of muscles and increase ability to have selective motor control.

group A: underwater exercise

Group BOther

Eligibility Criteria

Age9 Years - 12 Years

Sexall

Healthy VolunteersNo

Age GroupsChild (0-17)

You may not qualify if:

Children with non-spastic CP, orthopedic surgery for the lower extremities within the previous 12 months, botulinum toxin injections within the previous 6 months, fixed contractures or severe deformities, uncontrolled epilepsy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Middle East University
Othercollaborator
Emad Eldin Mohamed
Otherlead

Study Sites (1)

Bassam Ahmed Nabil

October 6 City, Cairo Governorate, 78345, Egypt

MeSH Terms

Conditions

Cerebral palsy, spastic, diplegicCerebral Palsy

Condition Hierarchy (Ancestors)

Brain Damage, ChronicBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Enrollment

60 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: DOUBLE
Who Masked: PARTICIPANT, INVESTIGATOR
Purpose: TREATMENT
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: SPONSOR INVESTIGATOR
PI Title: Associate professor

Study Record Dates

First Submitted

October 11, 2026

First Posted

October 16, 2026

Study Start

February 10, 2024

Actual (reported)

Comparative Effects of Under Water Exercise and Radial Extracorporeal Shockwave Therapy on Lower-Limb Spasticity, Gross Motor Function, and Quality of Life in Children With Spastic Diplegic Cerebral Palsy: A Randomized Controlled Trial

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (2)

Study Arms (2)

group A: underwater exercise

group B: radial extracorporeal shock wave therapy.

Interventions

Eligibility Criteria

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Enrollment

Study Design

Study Record Dates

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (2)

Study Arms (2)

group A: underwater exercise

group B: radial extracorporeal shock wave therapy.

Interventions

Eligibility Criteria

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Enrollment

Study Design

Study Record Dates

Source record

Locations