Peer Support for Family Caregivers of Older Adults Living With Dementia

NCT07868718 | Not Yet Recruiting Phase 2

• 2 other identifiers: STUDY202605861R01AG097585-01A1
• Study Type: interventional
• Target: 344
• Locations: 1 country
• Sites: 1

Brief Summary

Family caregivers of people living with dementia are at high risk of poor health when caregiving for their loved one. Peer Support for Family Caregivers of Older Adults Living with Dementia (Pair 2 Care©) is a simple, nonjudgmental, flexible, and potentially scalable peer support program developed with and for family caregivers along with former (previous) caregivers, community leaders, and healthcare providers. Using the experiences of trained former caregivers as mentors to current caregiver mentees, Pair 2 Care© may lower caregiver depressive symptoms and promote health and well-being of current caregivers, their loved ones, and former caregivers while informing future Alzheimer's disease and Alzheimer's disease-related dementia caregiving policy.

Conditions

Caregiver Burden; Caregiver Burnout; Caregiver Anxiety; Alzheimer Disease Dementia

Keywords

ADRD caregivers; virtual peer-delivered intervention; Depression; Caregiver, ADRD, dementia, dementia caregiving; anxiety

Outcome Measures

Primary Outcomes (1)

• Center for Epidemiologic Studies Depression Scale Revised (CESD-R-10)

  The Center for Epidemiologic Studies Depression Scale Revised (CESD-R-10) will be used to measure depressive symptoms.74 The CESD-R-10 is reliable (Cronbach's α = .86) and valid (convergent = .91; divergent = .89).

  Baseline, 3 months, 6 months

Study Arms (2)

Peer Support

EXPERIMENTAL

Former caregivers will be paired with a current caregivers

Behavioral: Peer Support

Active Control

ACTIVE COMPARATOR

Participants will receive usual care conditions

Behavioral: Usual Care

Interventions

Peer Support BEHAVIORAL

Former caregivers will be paired with a current caregiver based on a similar personal attribute (e.g., relationship to care recipient). Each pair will complete at least five virtual face-to-face (video) interactions and at least 10 other interactions either via phone call, email, or text messaging over the 6-month time period.

Peer Support

Usual Care BEHAVIORAL

Will include AD/ADRD and caregiving literature, as the control condition because it will provide a more real-world comparison. After completing the Month 6 data collection, they will be offered the Pair 2 Care intervention.

Active Control

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• English-speaking
• Adult (18+)
• Family Caregivers of people living with dementia (current or former)

You may not qualify if:

• Non-English-speaking
• Under age 18
• Non-family caregiver

Sponsors & Collaborators

• Ohio State University: lead
• National Institute on Aging (NIA): collaborator

Study Sites (1)

Ohio State University College of Nursing

Columbus, Ohio, 43210, United States

Location

MeSH Terms

Conditions

Caregiver Burden; Depression; Dementia; Anxiety Disorders

Condition Hierarchy (Ancestors)

Stress, Psychological; Behavioral Symptoms; Behavior; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurocognitive Disorders; Mental Disorders

Study Officials

• Karen O Moss, PhD

  Ohio State University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Karen O Moss, PhD

CONTACT

(614) 688-3100; Moss.391@osu.edu

Sandra L Solove, MA

CONTACT

614-247-8366; solove.3@osu.edu

Study Design

• Study Type: interventional
• Phase: phase 2
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Pair 2 Care is an innovative, award-winning, 6-month, 100% remote (face-to-face via video such as Zoom or FaceTime, telephone, email, and text message) peer support intervention designed with and for current and former Family Caregiver Participants (FCP) of high-risk people living with AD/ADRD. Trained former FCP mentors provide peer mentorship to current FCPs based on their caregiving experiences and per the study protocol. The PI and project manager will conduct bimonthly research team training blitzes, including interaction scenarios, to help ensure consistency in team member interactions with participants.

Study Record Dates

• First Submitted: October 5, 2026
• First Posted: October 9, 2026
• Study Start (Estimated): December 1, 2026
• Primary Completion (Estimated): August 1, 2031
• Study Completion (Estimated): August 1, 2031
• Last Updated: October 9, 2026

Record last verified: 2026-10

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)