NCT07866651|Not Yet Recruiting
Investigating Sex Differences in Mitochondrial Function and Leg Blood Flow During Exercise
MITOP
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MITOP
Sponsor study identifier
interventional
24
1 country
1
Study Start
October 2, 2026
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Primary Completion
March 27, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
May 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
This study will compare mitochondrial function and leg blood flow during exercise in healthy endurance-trained females and males aged 19-35.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
May 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 28, 2026
Actual (reported)October 2, 2026
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
October 8, 2026
Actual (reported)March 27, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
May 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Isolated mitochondria maximal state 3 respiration (pmols O2/microgram) measured via an ouroborous oxygraph (mitochondrial respirometry)
This measure quantifies the maximal rate of oxygen consumption (picomoles O2/ micogram of mitochondrial protein) when ADP, Malate, Succinate, Pyruvate and Glutamate have all been addded to the chamber.
Baseline
Maximal state 3 respiration in permeabilized Fibers (pmols O2/mg) measured via an ouroborous oxygraph (mitochondrial respirometry)
This measure quantifies the maximal rate of oxygen consumption (picomoles O2/ milligram of muscle tissue) when ADP, Malate, Succinate, Pyruvate and Glutamate have all been added to the chamber.
Baseline
Fiber type 1 specific maximal state 3 respiration (pmols O2/mg) measured via an ouroborous oxygraph (mitochondrial respirometry)
This measure quantifies the maximal rate of oxygen consumption (picomoles O2/ micogram of mitochondrial protein) when ADP, Malate, Succinate, Pyruvate and Glutamate have all been added to the chamber.
Baseline
Endurance Trained Healthy Males
Endurance Trained Healthy Females
Exercise - Men
Exercise - Females
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Gateway Health Building
Vancouver, British Columbia, V6T 1Z1, Canada
Cardinale DA, Larsen FJ, Schiffer TA, Morales-Alamo D, Ekblom B, Calbet JAL, Holmberg HC, Boushel R. Superior Intrinsic Mitochondrial Respiration in Women Than in Men. Front Physiol. 2018 Aug 17;9:1133. doi: 10.3389/fphys.2018.01133. eCollection 2018.
First Submitted
September 28, 2026
First Posted
October 8, 2026
Study Start
October 2, 2026
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Apply Biphasic IVM for POSEIDON Group 1
Fiber type 2 specific maximal state 3 respiration (pmols O2/mg) measured via an ouroborous oxygraph (mitochondrial respirometry)
This measure quantifies the maximal rate of oxygen consumption (picomoles O2/ micogram of mitochondrial protein) when ADP, Malate, Succinate, Pyruvate and Glutamate have all been addded to the chamber.
Baseline
Contact the study team to confirm eligibility.
Primary Completion
March 27, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
May 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
October 8, 2026
Record last verified: 2026-09
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Source: ClinicalTrials.gov.
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