Fit Accuracy of Maxillary and Mandibular Removable Partial Denture Frameworks Fabricated by Conventional Casting and Selective Laser Melting at a 0° Build Orientation: A Clinical Silicone-Replica Comparison
Sponsor study identifier
interventional
2
1 country
1
Study Start
September 15, 2025
Actual (reported)Primary Completion
November 30, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
November 30, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
This exploratory pilot clinical study evaluates the fit accuracy of cobalt-chromium removable partial denture (RPD) frameworks fabricated using conventional lost-wax casting and selective laser melting (SLM) at a 0° build orientation. Two partially edentulous participants with maxillary and mandibular Kennedy Class III modification 1 arches are included. Each participant receives four RPD frameworks: one conventionally cast and one 0° SLM framework for the maxillary arch, and one conventionally cast and one 0° SLM framework for the mandibular arch. Framework adaptation is evaluated using the silicone-replica technique and microscopic measurement of the gap between the framework and supporting oral structures at predefined locations. The study primarily compares framework fit between the two fabrication techniques and also explores differences between short- and long-edentulous-span sides and between maxillary and mandibular frameworks.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
November 30, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 15, 2025
Actual (reported)October 2, 2026
Actual (reported)October 7, 2026
Actual (reported)November 30, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
November 30, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Framework-to-Tissue Gap Distance by Fabrication Technique
Gap distance, expressed in micrometers (µm), between the fitting surface of each removable partial denture framework and the corresponding intraoral supporting structures, measured using the silicone-replica technique at predefined framework locations. Three microscopic readings are obtained at each location, and their mean is used as the gap value. Gap distances are compared descriptively between conventionally cast and 0° selective laser-melted frameworks under matched participant, arch, framework-component, and measurement-location conditions.
Immediately after clinical seating and adjustment of each framework, during the framework assessment visit.
Framework-to-Tissue Gap Distance by Edentulous-Span Length
Immediately after clinical seating and adjustment of each framework, during the framework assessment visit.
Framework-to-Tissue Gap Distance by Dental Arch
Immediately after clinical seating and adjustment of each framework, during the framework assessment visit.
Each participant receives both conventionally cast and 0° selective laser-melted cobalt-chromium removable partial denture frameworks for the maxillary and mandibular arches. For each arch, one framework is fabricated using the conventional lost-wax casting technique and one using selective laser melting at a 0° build orientation. Framework adaptation is assessed intraorally using the silicone-replica technique.
Cobalt-chromium removable partial denture framework fabricated using the conventional lost-wax casting technique. The framework is clinically seated, and its adaptation is evaluated using silicone-replica microscopic measurement at predefined framework locations.
Cobalt-chromium removable partial denture framework digitally designed and fabricated by selective laser melting at a 0° build orientation. The framework is clinically seated, and its adaptation is evaluated using silicone-replica microscopic measurement at predefined framework locations.
Faculty of Dentistry, Thamar University
Dhamar, Dhamār, 87246, Yemen
Gan N, Yao M, Ruan Y, Wang C, Xiong Y, Jiao T. Adaptation of maxillary removable partial denture frameworks fabricated with a direct digital workflow: A randomized crossover clinical trial. J Dent. 2025 Mar;154:105588. doi: 10.1016/j.jdent.2025.105588. Epub 2025 Jan 27.
Ye H, Ning J, Li M, Niu L, Yang J, Sun Y, Zhou Y. Preliminary Clinical Application of Removable Partial Denture Frameworks Fabricated Using Computer-Aided Design and Rapid Prototyping Techniques. Int J Prosthodont. 2017 Jul/Aug;30(4):348-353. doi: 10.11607/ijp.5270.
Radhwan Al-Gabri, PhD
IBB University
2 participants (actual enrollment reported by the registry).
First Submitted
October 2, 2026
First Posted
October 7, 2026
Study Start
September 15, 2025
Actual (reported)Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
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Chia VAP, See Toh YL, Quek HC, Pokharkar Y, Yap AU, Yu N. Comparative clinical evaluation of removable partial denture frameworks fabricated traditionally or with selective laser melting: A randomized controlled trial. J Prosthet Dent. 2024 Jan;131(1):42-49. doi: 10.1016/j.prosdent.2021.12.021. Epub 2022 Mar 5.
Elhadery SS, Alhajj MN, Yunus N, Ibrahim N, Abidin ZZ, Ahmad SF, Salleh NM. Adaptation of cobalt chromium frameworks fabricated by conventional versus selective laser melting techniques: An in vitro and clinical assessment. J Prosthet Dent. 2025 Nov;134(5):1836-1842. doi: 10.1016/j.prosdent.2024.03.020. Epub 2024 Apr 15.
Primary Completion
November 30, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
November 30, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
October 7, 2026
Record last verified: 2026-10
Deidentified individual participant data underlying the results reported in the published article will be available from the corresponding author upon reasonable request, subject to appropriate ethical and institutional considerations.
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Source: ClinicalTrials.gov.
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