Enhanced Recovery After Surgery (ERAS) Protocols on Postoperative Outcomes in Patients Undergoing Major Abdominal Procedures

NCT07855328 | Not Yet Recruiting DMC

• 1 other identifier: Allama Iqbal Teaching Hospital
• Study Type: interventional
• Target: 166
• Locations: 0 countries
• Sites: N/A

Brief Summary

ERAS protocols are still only partially and unevenly implemented in many hospitals in developing nations, despite substantial worldwide evidence to the contrary. Because of institutional regulations, lack of understanding, or budget constraints, local surgical units frequently stick to traditional perioperative care approaches. Furthermore, there is a dearth of local data assessing the viability and efficacy of ERAS protocols in patients undergoing significant abdominal surgeries in our healthcare settings. Thus, the purpose of this study is to evaluate how ERAS protocols affect the postoperative results of patients having major abdominal surgery at our facility. The study's findings will be useful in determining whether ERAS pathways will assist our patient population heal more quickly, experience fewer issues, and spend less time in the hospital. The results might potentially encourage the use of standardized ERAS procedures in surgical practice, which would enhance patient care and maximize the use of medical resources

Conditions

Abdominal Surgeries

Keywords

abdominal surgeries; ERAS; outcome

Outcome Measures

Primary Outcomes (2)

• Rate of Postoperative Complications

  Surgical site infection: superficial, deep, or organ-space infection diagnosed clinically by the treating surgeon or supported by wound findings, culture results, imaging, or the need for antibiotics or drainage. Anastomotic leak: clinical or radiological evidence of leakage from a surgical anastomosis, including feculent discharge from drain or wound, intra-abdominal collection related to anastomosis, or leak confirmed on imaging or reoperation. Ileus: failure of return of bowel function requiring continued nil per oral status, nasogastric decompression, or delayed oral intake beyond routine postoperative recovery as documented by the surgical team). As recorded in the patient's medical file, complications will be found by radiological results, laboratory tests, and clinical examinations

  30 days

• Mean hospital stay

  described as the total number of days between the day of surgery and the day of hospital discharge. For every patient, it will be computed in days and documented

  1 week

Study Arms (2)

ERAS

EXPERIMENTAL

Procedure: ERAS

Standard care

PLACEBO COMPARATOR

Procedure: Standard Care (in control arm)

Interventions

ERAS PROCEDURE

Patients managed by the surgical team according to the ERAS pathway will be included in Group A (ERAS group)

ERAS

Standard Care (in control arm) PROCEDURE

Patients managed according to routine conventional perioperative care during the study period will be included in Group B (conventional care group)

Standard care

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients of either gender between the ages of 18 and 70 years.
• Individuals having elective major abdominal surgery (such as small bowel resection, right hemicolectomy, left hemicolectomy, sigmoid colectomy, anterior resection, or similar colorectal resection).
• ASA class I-III patients

You may not qualify if:

• Patients who need to stay in the intensive care unit (ICU) after surgery for more than twenty-four hours.
• Individuals suffering from significant organ malfunction, such as advanced heart, liver, or kidney failure.
• Individuals who have had significant abdominal surgery within the recent three months.
• Patients who withdraw their consent or decline to participate in the study

Sponsors & Collaborators

• Dr Mudassar Saeed Pansota: lead

MeSH Terms

Interventions

Standard of Care

Intervention Hierarchy (Ancestors)

Quality Indicators, Health Care; Quality of Health Care; Health Services Administration; Health Care Quality, Access, and Evaluation

Study Officials

• muhammad ali armughan, MBBS

  Allama Iqbal Teaching Hospital, DG Khan

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Muhammad Ali Armughan, MBBS

CONTACT

03337950197; armughan915@gmail.com

mudassar saeed pansota, MS urology

CONTACT

03223044443; netygeulis749@hotmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: September 27, 2026
• First Posted: October 2, 2026
• Study Start: October 1, 2026
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): January 31, 2027
• Last Updated: October 2, 2026

Record last verified: 2026-09