NCT07851051

Brief Summary

8 participants including 2 pilots. The 2 pilot participants will each execute an MRI acquisition session in order to adjust the experimental paradigm

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
8

participants targeted

Target at below P25 for all trials

Timeline
49mo left

Started Sep 2025

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress20%
Sep 2025Sep 2030

Study Start

First participant enrolled

September 29, 2025

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

January 19, 2026

Completed
9 months until next milestone

First Posted

Study publicly available on registry

October 1, 2026

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 29, 2030

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 29, 2030

Last Updated

October 1, 2026

Status Verified

September 1, 2026

Enrollment Period

5 years

First QC Date

January 19, 2026

Last Update Submit

September 24, 2026

Conditions

Mental Health

Outcome Measures

Primary Outcomes (3)

  • Working memory performance - Cogmed

    Cognitive trajectories will be characterized using performance measures derived from the home-based training.

    5 week.

  • Working memory performance - CANTAB

    Cognitive trajectories will be characterized using performance measures derived from the Spatial Span (SSP) task from the CANTAB battery, administered under standardized conditions at GHU Paris Psychiatry and Neurosciences.

    2 week

  • Multimodal MRI data

    Multimodal MRI data - including anatomical, resting-state, working memory (WM) task-based functional, and diffusion-weighted sequences - will be acquired repeatedly over a six-week period during WM training, as well as before and after the training phase.

    2 week

Secondary Outcomes (2)

  • executive functions performance

    1 week

  • behavioral variables

    5 week for most variables

Eligibility Criteria

Age18 Years - 30 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

healthy adult volunteers aged 18 to 30 who have no contraindications to an MRI scan.

You may qualify if:

  • age between 18 and 30 years,
  • right-handedness (assessed using the Edinburgh Handedness Inventory),
  • native French speaker, affiliation with the French national health insurance system
  • provision of written informed consent prior to participation.

You may not qualify if:

  • contraindications to MRI,
  • neurological or psychiatric disorders
  • history of traumatic brain injury
  • any geographical or psychological condition preventing full compliance with the study protocol.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CACHIA

Paris, 75014, France

RECRUITING

MeSH Terms

Conditions

Psychological Well-Being

Condition Hierarchy (Ancestors)

Personal SatisfactionBehavior

Study Officials

  • CACHIA Arnaud

    hospital saint anne of the GHU Paris

    PRINCIPAL INVESTIGATOR

Central Study Contacts

CACHIA Arnaud

CONTACT

0661519200arnaud.cachia@u-paris.fr

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
OTHER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 19, 2026

First Posted

October 1, 2026

Study Start

September 29, 2025

Primary Completion (Estimated)

September 29, 2030

Study Completion (Estimated)

September 29, 2030

Last Updated

October 1, 2026

Record last verified: 2026-09

Locations

FR(1)