Platelet Indices and Blood Groups in Type 2 Diabetes Vascular Complications

NCT07847099 | Not Yet Recruiting

• 1 other identifier: Platelet-T2DM-Assiut-2026
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

This cross-sectional study aims to evaluate the association of platelet indices and ABO blood groups with vascular complications in patients with type 2 diabetes mellitus.

Conditions

Type 2 Diabetes Mellitus; Vascular Complications

Keywords

Platelet indices; MPV; Type 2 diabetes; ABO blood group; Assiut

Outcome Measures

Primary Outcomes (1)

• Mean platelet volume in patients with and without vascular complications

  Mean platelet volume (MPV) in femtoliters compared between type 2 diabetes patients with vascular complications and those without vascular complications.

  Baseline

Secondary Outcomes (5)

• Mean platelet distribution width

  Baseline

• Distribution of ABO blood groups according to vascular complications

  Baseline

• Mean platelet volume according to ABO blood group

  Baseline

• Prevalence of microvascular complications

  Baseline

• Prevalence of macrovascular complications

  Baseline

Study Arms (2)

T2DM with Vascular Complications

Patients with type 2 diabetes mellitus who have microvascular or macrovascular complications.

T2DM without Vascular Complications

Patients with type 2 diabetes mellitus who have no microvascular or macrovascular complications.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients with type 2 diabetes mellitus attending the Internal Medicine Department and Diabetes Center at Assiut University Hospital.

You may qualify if:

• Age 18 years or older
• Confirmed diagnosis of type 2 diabetes mellitus according to ADA criteria
• Written informed consent

You may not qualify if:

• Type 1 diabetes mellitus
• Gestational diabetes
• Acute infection or sepsis
• Hematological disorders affecting platelet count or function
• Malignancy
• Chronic liver disease
• Autoimmune diseases
• Current anticoagulant or antiplatelet therapy
• Recent major surgery or trauma
• Pregnancy

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Condition Hierarchy (Ancestors)

Diabetes Mellitus; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Study Officials

• Lobna F El-toony

  Internal Medicine Department, Assiut University Hospitals

  STUDY CHAIR

Central Study Contacts

Nehla S Mohamed, Resident

CONTACT

01023327969; Nehal.18313533@med.aun.edu.eg

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident Physician, Department of Internal Medicine

Study Record Dates

• First Submitted: September 23, 2026
• First Posted: September 29, 2026
• Study Start: September 26, 2026
• Primary Completion (Estimated): September 26, 2027
• Study Completion (Estimated): March 25, 2028
• Last Updated: September 29, 2026

Record last verified: 2026-09

Data Sharing

• IPD Sharing: Will not share