Comparative Study of Ultrasound Guided Superficial vs Intermediate Cervical Plexus Block for Perioperative Analgesia in Thyroid Surgeries.

NCT07843589 | Recruiting DMC

• 1 other identifier: 9/2026ANET7
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

The investigator compare the analgesic efficacy of ultrasound-guided subcutaneous cervical plexus block vs ultrasound-guided intermediate cervical plexus block pre-intra and postoperative thyroid surgery

Conditions

Thyroid Surgeries

Outcome Measures

Primary Outcomes (1)

• Postoperative VAS scores

  The postoperative VAS scores at 0 (just after extubation), 2, 4, 6, 12, 18 and 24 hours.

  VAS scores at 0 (just after extubation), 2, 4, 6, 12, 18 and 24 hours.

Secondary Outcomes (2)

• Total dose of rescue analgesic required

  first 24 hours

• Diaphragmatic excursion measured by ultrasound M-mode

  30 minutes after the block and after endotracheal extubation

Study Arms (2)

Ultrasound guided subcutaneous superficial cervical plexus block

ACTIVE COMPARATOR

Procedure: Ultrasound guided superficial cervical plexus block

Ultrasound guided intermediate cervical plexus block

ACTIVE COMPARATOR

Procedure: ultrasound guided intermediate cervical plexus block

Interventions

Ultrasound guided superficial cervical plexus block PROCEDURE

Ultrasoundguided subcutaneous superficial cervical plexus block. The linear probe will be placed transversely over the lateral side of the neck at the midpoint of the posterior border of the sternocleidomastoid muscle (SCM) such that the tapering end (posterior border on the ultrasound image) of the SCM comes to the center of the screen. After infiltrating the skin with 1 mL of 2% lignocaine, the needle will be introduced from the posterior aspect through the skin and platysma where 10 mL of 0.25% bupivacaine with 5 µg/mL of epinephrine (50 µg) and 100 µg dexmedetomidine (with concentration of 200µg/2ml) diluted in 2 ml saline) will be deposited just behind this landmark to give a single point subcutaneous superficial cervical plexus block. Block will be repeated on the other side as well

Ultrasound guided subcutaneous superficial cervical plexus block

ultrasound guided intermediate cervical plexus block PROCEDURE

The transducer probe will be placed transversely over the midpoint of the sternocleidomastoid muscle such that the tapering posterior edge was positioned in the middle of the screen (at the level of the cricoid cartilage, where the external jugular vein crosses sternocleidomastoid). With the in-plane technique, after infiltrating the skin with 1 mL of 2% lignocaine, the block needle will be advanced adjacent to the superficial cervical plexus in the plane deep to sternocleidomastoid, underneath the investing fascia (sternocleidomastoid-trapezius fascia) and immediately above the interscalene groove \[Figure 3\]. After negative aspiration, 10 mL of 0.25% bupivacaine with 5 µg/mL of epinephrine (50 µg) and 100 µg dexmedetomidine (with concentration of 200µg/2ml) diluted in 2 ml saline) will be deposited under the fascia after feeling the click or 'pop' on piercing this fascia. The same formulation will be given on the other side as well.

Ultrasound guided intermediate cervical plexus block

Eligibility Criteria

• Age: 20 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patients with ASA physical status 1 or 2 and 3
• Patients undergoing elective total thyroidectomy (with normal thyroid function tests)
• Patients aged 20 to 60 years of both sexes

You may not qualify if:

• Patients with known bleeding diathesis
• History of allergy to local anaesthetics or known diaphragmatic motion abnormalities
• Patient who refuse to participate
• BMI (Body Mass Index) more than 35 kg/m2
• Previous neck surgeries/Burns injury to neck/ contractures in neck
• Patients with known seizure disorder
• Patients with history of radiation exposure on neck.

Sponsors & Collaborators

• Menoufia University: lead

Study Sites (1)

Faculty of medicine Menoufia University

Alexandria, Shebin Elkom, Egypt

RECRUITING

Central Study Contacts

Nevine Soliman, MD

CONTACT

201128861471; mostafanevine@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor of anesthesia

Study Record Dates

• First Submitted: September 21, 2026
• First Posted: September 28, 2026
• Study Start: October 1, 2026
• Primary Completion (Estimated): March 1, 2027
• Study Completion (Estimated): May 1, 2027
• Last Updated: September 29, 2026

Record last verified: 2026-09

Locations

EG (1)