Hybrid III Trial of Automated Referral to Comprehensive Geriatric Assessment for Frail Older Surgical Patients

NCT07836959 | Not Yet Recruiting FDA Device

• 3 other identifiers: 2026-0832UWMSN | SMPH | Surgery - ColonProtocol Version 5/29/26
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to learn about automated referrals to Perioperative Optimization of Senior Health (POSH). The main question it aims to answer is:

• Do automated referrals to POSH increase the number of people who attend the clinic?

Conditions

Elective Surgery; Frail Elderly

Outcome Measures

Primary Outcomes (2)

• Number of participants who attend POSH

  The number of eligible participants who attend POSH will be compared across arms.

  90 days

• Number of surgeons who refer to POSH

  The number of surgeons who refer patients to POSH will be compared to those in the same clinical departments for both arms.

  90 days

Secondary Outcomes (4)

• Anticholinergic Burden Score

  90 days

• Documentation of preoperative cognitive status

  90 days

• Physical therapy (PT) referrals

  90 days

• Advanced care planning (ACP) on file

  90 days

Study Arms (2)

Automated referrals

EXPERIMENTAL

Participants will receive an automated referral to POSH when screened by the electronic frailty index (a clinical decision support device built into the EHR)

Device: Automated referral

Usual care

ACTIVE COMPARATOR

Participants will receive usual care in which surgeons can choose to directly refer patients to POSH.

Other: Usual Care Group

Interventions

Usual Care Group OTHER

Surgeons will be notified of frailty score (as calculated using the frailty score calculator device embedded in the EHR). Surgeons can choose to refer patients directly to POSH.

Usual care

Automated referral DEVICE

Participants who screen for frailty (using the frailty score calculator device embedded in the EHR) will receive an automated referral to POSH clinic through their electronic health record.

Automated referrals

Eligibility Criteria

• Age: 80 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)

You may qualify if:

• Age 80 or older
• Scheduled for an elective surgery with a planned overnight stay
• Scores indicate frailty

You may not qualify if:

• Scheduled for transplant or cardiothoracic surgery
• Undergoing emergency or urgent surgery
• POSH clinic evaluation within the past 6 months

Sponsors & Collaborators

• University of Wisconsin, Madison: lead

Study Sites (1)

University of Wisconsin

Madison, Wisconsin, 53792, United States

Location

Study Officials

• Julia Berian

  University of Wisconsin, Madison

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Randi Cartmill

CONTACT

608-263-9316; cartmill@wisc.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 17, 2026
• First Posted: September 23, 2026
• Study Start (Estimated): November 1, 2026
• Primary Completion (Estimated): October 1, 2027
• Study Completion (Estimated): October 1, 2027
• Last Updated: September 29, 2026

Record last verified: 2026-09

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ANALYTIC CODE
• Time Frame: Scientific data will be available once the primary results are published. Data will be available indefinitely.
• Access Criteria: Data are available on request from the principal investigator with a DUA. Supporting materials will be available on a public website that will be created for this purpose.

Locations

US (1)