NCT07833449

Brief Summary

This randomized controlled trial evaluates the effect of Quranic recitation (murottal) on psychosomatic symptoms and fatigue in adults living with HIV who have psychosomatic symptoms and fatigue. Participants are randomly assigned to either the intervention group, which receives Quranic recitation for approximately 15 minutes, three times per week for 30 days, or the control group. Psychosomatic symptoms and fatigue are assessed before and after the intervention using the Shatri-Sinulingga Psychosomatic Test (SSPT) and Fatigue Severity Scale (FSS), respectively.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started May 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 20, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 12, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 12, 2026

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

September 16, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

September 22, 2026

Completed
Last Updated

September 22, 2026

Status Verified

September 1, 2026

Enrollment Period

2 months

First QC Date

September 16, 2026

Last Update Submit

September 16, 2026

Conditions

Psychosomatic SymptomsFatigue Symptom

Outcome Measures

Primary Outcomes (2)

  • Change in Shatri-Sinulingga Psychosomatic Test (SSPT) Score

    Baseline to 30 days after randomization

  • Change in Fatigue Severity Scale (FSS) Score

    Baseline to 30 days after randomization

Study Arms (2)

Murottal Quran

EXPERIMENTAL

15 mins/ 3 times a week for 30 days

Behavioral: Quranic Recitation (Murottal)

Control

NO INTERVENTION

Standard care without murottal intervention

Interventions

Quranic Recitation (Murottal)BEHAVIORAL

Participants receive Quranic recitation (murottal) for approximately 15 minutes, three times per week for 30 days (12 sessions).

Murottal Quran

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adults aged ≥18 years. Diagnosed with human immunodeficiency virus (HIV) infection. Muslim. HIV clinical stage 1-2. Undetectable HIV viral load. Shatri-Sinulingga Psychosomatic Test (SSPT) score ≥2. Fatigue Severity Scale (FSS) score ≥36. Willing to participate in the study and provide informed consent.

You may not qualify if:

  • Severe hearing impairment or inability to follow the intervention procedure. Psychotic disorder or depressive disorder requiring psychiatric medication. Pregnancy. Active opportunistic infection. Refusal to participate in the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

RSUPN Dr. Cipto Mangunkusumo

Jakarta, DKI Jakarta, 10430, Indonesia

Location

Related Publications (5)

  • Majidi H, Rajabi-Tavakkol A. A Systematic Review of EEG Studies on the Neural Effects of Quran Listening. Iran J Psychiatry. 2025 Apr;20(2):253-264. doi: 10.18502/ijps.v20i2.18206.

    PMID: 40521283RESULT

  • Babamohamadi H, Sotodehasl N, Koenig HG, Al Zaben F, Jahani C, Ghorbani R. The Effect of Holy Qur'an Recitation on Depressive Symptoms in Hemodialysis Patients: A Randomized Clinical Trial. J Relig Health. 2017 Feb;56(1):345-354. doi: 10.1007/s10943-016-0281-0.

    PMID: 27393704RESULT

  • Babamohamadi H, Sotodehasl N, Koenig HG, Jahani C, Ghorbani R. The Effect of Holy Qur'an Recitation on Anxiety in Hemodialysis Patients: A Randomized Clinical Trial. J Relig Health. 2015 Oct;54(5):1921-30. doi: 10.1007/s10943-014-9997-x.

    PMID: 25559332RESULT

  • Barroso J, Leserman J, Harmon JL, Hammill B, Pence BW. Fatigue in HIV-Infected People: A Three-Year Observational Study. J Pain Symptom Manage. 2015 Jul;50(1):69-79. doi: 10.1016/j.jpainsymman.2015.02.006. Epub 2015 Feb 18.

    PMID: 25701691RESULT

  • Shatri H, Sinulingga DI, Faisal E, Irvianita V, Putranto R, Ardani Y, Erlita D, Jeger DP, Browijoyo IA. Validity and reliability testing of the Shatri Sinulingga psychosomatic test (SSPT) questionnaire as a screening instrument for psychosomatic disorders in Indonesia. Narra J. 2024 Dec;4(3):e1373. doi: 10.1042/narra.v4i3.1373. Epub 2024 Nov 8.

    PMID: 39816117RESULT

MeSH Terms

Conditions

Fatigue

Condition Hierarchy (Ancestors)

Signs and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Internal Medicine Specialist / Internal Medicine Resident (PPDS)

Study Record Dates

First Submitted

September 16, 2026

First Posted

September 22, 2026

Study Start

May 20, 2026

Primary Completion

July 12, 2026

Study Completion

July 12, 2026

Last Updated

September 22, 2026

Record last verified: 2026-09

Data Sharing

IPD Sharing
Will not share

Locations

ID(1)