Risk Factors of Venous Thrombotic Event in Interstitial Lung Disease

NCT07833254 | Not Yet Recruiting

• 1 other identifier: Soh-Med-26-7-21MS
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to determine the incidence of venous thromboembolic events (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), among hospitalized patients with interstitial lung disease (ILD). It will also identify potential risk factors associated with VTE and evaluate its impact on clinical outcomes. Patients with ILD admitted to the hospital will be assessed for clinical characteristics, disease severity, risk factors for thrombosis, and the occurrence of DVT or PE during hospitalization. The study findings may help improve early recognition of VTE and guide appropriate preventive and diagnostic strategies in hospitalized patients with ILD.

Conditions

Pulmonary Embolism; Deep Venous Thrombosis; Interstitial Lung Disease; Venous Thromboembolism

Outcome Measures

Primary Outcomes (1)

• Primary outcome: Incidence of venous thromboembolic events (VTE)

  Number and proportion of adult patients with ILD who develop objectively confirmed venous thromboembolic events, defined as DVT and/or pulmonary embolism, during hospitalization.

  One Year

Secondary Outcomes (4)

• Length of hospital stay

  One year

• Requirement and level of respiratory support

  One Year

• ICU admission and length of ICU stay

  One Year

• In-hospital mortality

  One Year

Study Arms (1)

One group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

"The study will include adult patients aged 18 years or older who are admitted to the Department of Chest Diseases, Sohag University Hospital, with a confirmed diagnosis of interstitial lung disease (ILD). Eligible patients will be assessed for risk factors, clinical characteristics, and occurrence of venous thrombotic events during hospitalization.

You may qualify if:

• Age ≥ 18 years. Patients admitted to the respiratory ICU, Chest Department

You may not qualify if:

• Age \< 18 years. Patients already receiving therapeutic anticoagulation before admission. Known inherited thrombophilia. Active malignancy. Pregnancy. Patients refusing participation. Recent major surgery or trauma within previous 4 weeks.

Sponsors & Collaborators

• Sohag University: lead

MeSH Terms

Conditions

Lung Diseases, Interstitial; Venous Thromboembolism; Pulmonary Embolism; Venous Thrombosis

Condition Hierarchy (Ancestors)

Lung Diseases; Respiratory Tract Diseases; Thromboembolism; Embolism and Thrombosis; Vascular Diseases; Cardiovascular Diseases; Embolism; Thrombosis

Central Study Contacts

Basant MA Omer, M.BB.Ch.

CONTACT

01027894838; Basant.Mahmoud@med.sohag.edu.eg

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident of chest diseases

Study Record Dates

• First Submitted: September 5, 2026
• First Posted: September 22, 2026
• Study Start: September 1, 2026
• Primary Completion (Estimated): August 31, 2027
• Study Completion (Estimated): August 31, 2027
• Last Updated: September 22, 2026

Record last verified: 2026-09