Same-Day Discharge After Elective Transradial Percutaneous Coronary Intervention: A Pilot Randomized Trial

NCT07830784 | Completed

• 3 other identifiers: SDD-PROCAPE-202588019325.1.0000.51927.667.758
• Study Type: interventional
• Target: 58
• Locations: 1 country
• Sites: 1

Brief Summary

This single-center pilot randomized trial evaluated the safety and feasibility of same-day discharge (within 6 hours) compared with conventional overnight hospitalization (≥24 hours) in patients with chronic coronary artery disease undergoing successful elective transradial PCI in a Brazilian public tertiary center. Participants were followed by structured telemedicine consultation at 7 days.

Conditions

Coronary Artery Disease; Chronic Coronary Syndrome; Elective Percutaneous Coronary Intervention

Keywords

same-day discharge; transradial access; elective PCI; telemedicine; public healthcare system

Outcome Measures

Primary Outcomes (1)

• Composite of major adverse clinical events

  All-cause death, myocardial infarction, unplanned revascularization, stroke, hospital readmission, or major bleeding (BARC ≥3)

  7 days after PCI

Secondary Outcomes (3)

• Emergency department visits

  7 days after PCI

• Recurrent chest pain

  7 days after PCI

• Radial access-site complications

  7 days after PCI

Study Arms (2)

Same-Day Discharge

EXPERIMENTAL

discharge within 6 h after successful elective transradial PCI, with 7-day telemedicine follow-up.

Behavioral: same day discharge

Conventional Hospitalization

ACTIVE COMPARATOR

overnight stay ≥24 h per institutional protocol.

Behavioral: Conventional Hospitalization

Interventions

same day discharge BEHAVIORAL

discharge within 6 h after successful elective transradial PCI, with 7-day telemedicine follow-up.

Same-Day Discharge

Conventional Hospitalization BEHAVIORAL

overnight stay ≥24 h per institutional protocol.

Conventional Hospitalization

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults ≥18 with chronic CAD undergoing successful elective transradial PCI; written informed consent.

You may not qualify if:

• LVEF ≤40%; MI within 14 days; creatinine clearance ≤45 mL/min; hemoglobin ≤10 g/dL; platelets ≤100,000/µL; INR \>1.5; allergy to aspirin, clopidogrel, or iodinated contrast; procedural (angiographic or clinical) complications; access-site complications requiring prolonged monitoring.

Sponsors & Collaborators

• PAULO CASTRO CHERPAK: lead

Study Sites (1)

PROCAPE

Recife, Pernambuco, Brazil

Location

MeSH Terms

Conditions

Coronary Artery Disease

Condition Hierarchy (Ancestors)

Coronary Disease; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases

Study Officials

• Audes D Feitosa, PhD

  University of Pernambuco

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: September 10, 2026
• First Posted: September 21, 2026
• Study Start: July 4, 2025
• Primary Completion: December 29, 2025
• Study Completion: December 29, 2025
• Last Updated: September 21, 2026

Record last verified: 2026-09

Data Sharing

• IPD Sharing: Will share

Locations

BR (1)