NCT07829159

Brief Summary

We are going to test the bacteria growing in your intestine to see if they can influence your ability to manage stress while flying an airplane.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
1mo left

Started Sep 2026

Shorter than P25 for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress54%
Sep 2026Nov 2026

Study Start

First participant enrolled

September 1, 2026

Completed
13 days until next milestone

First Submitted

Initial submission to the registry

September 14, 2026

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 18, 2026

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 30, 2026

Expected
2 days until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2026

Last Updated

September 18, 2026

Status Verified

September 1, 2026

Enrollment Period

2 months

First QC Date

September 14, 2026

Last Update Submit

September 14, 2026

Conditions

Outcome Measures

Primary Outcomes (2)

  • Microbial activity relationship to stress tolerance.

    Correlation of microbiome with stress tolerance in flight simulation.

    30 minute simulation

  • Microbial metabolic pathways

    We will evaluate the correlation between microbial strains and their metabolic activity with the ability to handle stressful situations in a flight simulator.

    30 minute simulation.

Study Arms (1)

Pilots

18-25 year old aviation students

Behavioral: Flight simulator

Interventions

Use of flight simulator

Also known as: Aeronautical Simulation
Pilots

Eligibility Criteria

Age18 Minutes - 25 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodProbability Sample
Study Population

Healthy licensed instrument rated pilots.

You may qualify if:

  • Healthy instrument rated pilot

You may not qualify if:

  • Mental illness, chronic inflammatory disease, gastrointestinal disease.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Officials

  • Alison Adams, MS

    UNO

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Jon Vanderhoof, MD

CONTACT

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Instructor

Study Record Dates

First Submitted

September 14, 2026

First Posted

September 18, 2026

Study Start

September 1, 2026

Primary Completion (Estimated)

October 30, 2026

Study Completion (Estimated)

November 1, 2026

Last Updated

September 18, 2026

Record last verified: 2026-09