NCT07825532

Brief Summary

This study has for goal to evaluate vascularised fibula flap and induced membrane for children's bone loss.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
140

participants targeted

Target at P50-P75 for all trials

Timeline
3mo left

Started Sep 2026

Shorter than P25 for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress18%
Sep 2026Dec 2026

First Submitted

Initial submission to the registry

September 5, 2026

Completed
10 days until next milestone

Study Start

First participant enrolled

September 15, 2026

Completed
2 days until next milestone

First Posted

Study publicly available on registry

September 17, 2026

Completed
14 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2026

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2026

Expected
Last Updated

September 17, 2026

Status Verified

September 1, 2026

Enrollment Period

16 days

First QC Date

September 5, 2026

Last Update Submit

September 11, 2026

Conditions

Bone LossReconstructionChildrenInduced MembraneFibula FlapMicrosurgery

Outcome Measures

Primary Outcomes (1)

  • Complete consolidation at 12 months

    The measures will be evaluated on x-rays. Consolidation is considerred achieved when at least 3 out of 4 cortices are fused. Xrays are done on every consultations

    assessment of consolidation 12 months after surgical reconstruction, for induced membrane group the first time of surgery is considerred

Interventions

limb reconstructionPROCEDURE

* induced membrane * vascularised fibula

Eligibility Criteria

Age0 Years - 18 Years
Sexall
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Children from 0 to 18 years.

You may qualify if:

  • Patient under 18 years old
  • Procedure by induced membrane or vascularised fibula flap for limb reconstruction from 2000 to 2026

You may not qualify if:

  • Patient under 6 months follow up
  • Patient who underwent vascularised fibula flap with epiphysis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Bone Diseases, Metabolic

Condition Hierarchy (Ancestors)

Bone DiseasesMusculoskeletal DiseasesMetabolic DiseasesNutritional and Metabolic Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Orthopedic surgeon

Study Record Dates

First Submitted

September 5, 2026

First Posted

September 17, 2026

Study Start

September 15, 2026

Primary Completion

October 1, 2026

Study Completion (Estimated)

December 31, 2026

Last Updated

September 17, 2026

Record last verified: 2026-09

Data Sharing

IPD Sharing
Will not share