Pattern and Surgical Outcome of Papillary Thyroid Cancer at Sohag University Hospitals

NCT07823439 | Not Yet Recruiting

• 1 other identifier: Soh-Med-26-7-15MS
• Study Type: observational
• Target: 30
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this study is to evaluate the clinicopathological pattern and surgical outcome of papillary thyroid carcinoma (PTC) at Sohag University Hospitals. This will help improve local risk stratification, optimize surgical decision-making, and guide future management strategies for patients with PTC in this region.

Conditions

Papillary Thyroid Carcinoma; Thyroid Cancer

Keywords

papillary thyroid carcinoma; thyroidectomy; neck dissection; surgical outcomes; clinicopathological pattern

Outcome Measures

Primary Outcomes (1)

• Prevalence of Extrathyroidal Extension in Papillary Thyroid Carcinoma

  Percentage of participants with histologically confirmed extrathyroidal extension.

  9 months

Secondary Outcomes (3)

• Incidence of Early Postoperative Surgical Complications

  9 months

• Incidence of Multifocal Papillary Thyroid Carcinoma

  9 months

• Rate of Cervical Lymph Node Metastasis

  9 months

Study Arms (1)

patients with papillary thyroid carcinoma

All patients diagnosed with papillary thyroid carcinoma (and its variants) managed at Sohag University Hospitals during the study period (June 2023 to March 2027).

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients diagnosed with papillary thyroid carcinoma (PTC) who are admitted and managed at the Department of General Surgery, Sohag University Hospitals, serving as a tertiary care center in Upper Egypt.

You may qualify if:

• All patients diagnosed with papillary thyroid carcinoma and its variants managed at Sohag University Hospitals.
• Confirmation of diagnosis histopathologically.
• Availability of sufficient clinical, radiological, operative, and pathological data for analysis.

You may not qualify if:

• Patients diagnosed with other types of thyroid malignancy (e.g., follicular, medullary, or anaplastic carcinoma).
• Patients with a history of previous thyroid surgery before presentation to the study setting.
• Patients with incomplete essential medical records that prevent confirmation of diagnosis or extraction of main study variables.

Sponsors & Collaborators

• Sohag University: lead

Biospecimen

Retention: SAMPLES WITHOUT DNA

Formalin-fixed paraffin-embedded (FFPE) tissue blocks and histopathological slides of resected thyroid specimens.

MeSH Terms

Conditions

Thyroid Cancer, Papillary; Thyroid Neoplasms

Condition Hierarchy (Ancestors)

Adenocarcinoma, Papillary; Adenocarcinoma; Carcinoma; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type; Neoplasms; Endocrine Gland Neoplasms; Neoplasms by Site; Head and Neck Neoplasms; Endocrine System Diseases; Thyroid Diseases

Central Study Contacts

Ahmed Aboulabed Resident Ahmed Aboulabed Ahmed Mousa, resident

CONTACT

01114522110; ahmed.aboulabed@yahoo.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident Physician, Department of General Surgery, Sohag University Hospitals

Study Record Dates

• First Submitted: August 25, 2026
• First Posted: September 16, 2026
• Study Start: September 16, 2026
• Primary Completion (Estimated): March 1, 2027
• Study Completion (Estimated): March 1, 2027
• Last Updated: September 16, 2026

Record last verified: 2026-08