Clinicoradiological Correlation Between Long Standing Untreated Adenoids and Nasal Septum Deviation in Adolescents

NCT07816042 | Not Yet Recruiting

• 1 other identifier: nasal Septum Deviation
• Study Type: observational
• Target: 50
• Locations: 0 countries
• Sites: N/A

Brief Summary

The adenoids, also known as pharyngeal tonsils, are the peripheral immune organs of the human body and are located at the junction of the nasopharyngeal parietal and posterior walls. The adenoids represent the first defense portal of the respiratory tract and the earliest site of exposure to various antigens by inhalation or ingestion This can result in adenoid hypertrophy (AH) due to repeated stimulation by various antigens and their own inflammation (1) . AH is the chronic enlargement of the adenoids usually accompanied by recurrent infections. Adenoids which are enlarged are capable of becoming practically the ping pong ball sized and wholly obstruct airflow in the course of nasal cavities (2) . AH is commonly encountered in children and is a well-recognized cause of nasal obstruction. Typically, the tissue undergoes involution during adolescence, and its persistence into adulthood is considered unusual. However, AH in adolescents is thought to be a persistence of untreated AH of childhood (3) In such cases, persistent adenoid hypertrophy may continue to cause chronic nasal obstruction and prolonged mouth breathing. Mouth breathing alters the normal functional balance between the tongue, lips, and buccal muscles, which may contribute to narrowing of the maxillary arch and development of a high-arched palate during childhood growth. If adenoid hypertrophy and nasal obstruction remain untreated, these functional and structural changes may persist into adolescence (4) . As the hard palate forms the floor of the nasal cavity, a high-arched palate and associated maxillary changes may alter the shape and available space of the nasal cavity. Such anatomical changes may

• may influence the configuration of the nasal septum, particularly during the growing years, 2 providing a possible structural link between long-standing adenoid hypertrophy and septal deviation (5) Despite the recognized effects of chronic adenoid obstruction on nasal breathing and craniofacial development, evidence specifically addressing whether long-standing untreated AH is associated with septal deviation remains limited. so, this study aims to investigate the clinicoradiological correlation between long-standing untreated AH and nasal septal deviation in adolescent

Conditions

Nasal Septum Deviation

Outcome Measures

Primary Outcomes (1)

• Degree of nasal septal deviation in relation to the presence and size of longstanding untreated adenoid hypertrophy

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Study Arms (1)

study group

patients with chronic nasal obstruction

Eligibility Criteria

• Age: 10 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

patients with chronic nasal obstruction

You may qualify if:

• Age 10 to18 years. Both sexes. Adolescents with long standing untreated adenoid hypertrophy. Presence of symptoms suggestive of chronic nasal obstruction, such as mouth breathing, nasal obstruction, or snoring

You may not qualify if:

• Previous adenoidectomy or nasal surgery. History of significant nasal trauma or nasal fracture. Congenital craniofacial anomalies. Chronic sinonasal diseases that may independently cause significant nasal obstruction. Patients who disagreed to participate in the study

Sponsors & Collaborators

• Assiut University: lead

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: residant doctor at Assiut university hospital

Study Record Dates

• First Submitted: September 7, 2026
• First Posted: September 11, 2026
• Study Start: October 1, 2026
• Primary Completion (Estimated): October 1, 2027
• Study Completion (Estimated): December 1, 2027
• Last Updated: September 11, 2026

Record last verified: 2026-09