NCT07808801

Brief Summary

In French Guiana, Indigenous people experience high levels of psychological distress and higher rates of suicidal behavior than the rest of the population. The Wayãpi and Teko communities living in Camopi and Trois-Sauts are particularly affected. Since 2025, Community Workers (CHWs) from these communities have been appointed to facilitate access to care, improve communication between residents and health services, and strengthen support in situations of distress. To date, no scientific evaluation has been conducted to measure the actual impact of this initiative. This research therefore aims to better understand mental health in these communities and to assess the effect of the community mediators' work. The results will help improve suicide prevention efforts and adapt public health policies to local realities. The purpose of this study is to assess the impact of CHWs activities on:

  • suicidal behavior,
  • psychological distress,
  • alcohol use,
  • use of health care services, within the Wayãpi and Teko communities of Camopi and Trois-Sauts.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
35mo left

Started Sep 2026

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress3%
Sep 2026Aug 2029

Study Start

First participant enrolled

September 1, 2026

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

September 2, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

September 9, 2026

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 30, 2029

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 30, 2029

Last Updated

September 9, 2026

Status Verified

August 1, 2026

Enrollment Period

3 years

First QC Date

September 2, 2026

Last Update Submit

September 2, 2026

Conditions

Keywords

Indigenous mental healthSuicide preventionCommunity Health WorkersAmazonia / French GuianaIntercultural mediation

Outcome Measures

Primary Outcomes (1)

  • Change in the incidence of suicidal behaviours (suicidal ideation, suicide attempts, and suicide deaths) in the villages of Camopi and Trois-Sauts before and after the deployment of CHWs

    Change in the incidence of suicidal behaviours (suicidal ideation, suicide attempts, and suicide deaths) in the study population, comparing retrospective suicidal behaviour rates in the 5 years before with propective suicidal behaviour rates at 12, 24 and 30 months after the intervention of CHWs among the study population

    From inclusion to 12, 24 and 30 months after CHWs intervention

Secondary Outcomes (7)

  • Prevalence of psychological distres

    From inclusion to 12, 24 and 30 months

  • Prevalence of alcohol use pattern

    From inclusion to 12, 24 and 30 months

  • Health-care utilisation

    From inclusion to 12, 24 and 30 months

  • Cultural representations of mental health and CHWs intervention

    From inclusion to 12, 24 and 30 months

  • Community perceptions of mental health and of CHWs intervention

    From inclusion to 12, 24 and 30 months

  • +2 more secondary outcomes

Eligibility Criteria

Age12 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adults and children over 12 years of age from the Wayapi and Teko communities in the villages of Camopi and Trois-Saut in French Guiana

You may qualify if:

  • Age \> 12 years
  • Members of the Wayãpi or Teko communities residing in Camopi or Trois-Sauts.
  • No objection to participating in the study and to the use of their data after receiving information in local languages and in French

You may not qualify if:

  • Individuals under legal guardianship
  • Health conditions that prevent them from understanding or completing questionnaires or participating in interviews.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Centre Hospitalier de Cayenne

Cayenne, French Guiana, 97300, French Guiana

Location

Related Publications (7)

  • Pollock NJ, Naicker K, Loro A, Mulay S, Colman I. Global incidence of suicide among Indigenous peoples: a systematic review. BMC Med. 2018 Aug 20;16(1):145. doi: 10.1186/s12916-018-1115-6.

  • Pacot R, Garmit B, Pradem M, Nacher M, Brousse P. The problem of suicide among Amerindians in Camopi-Trois Sauts, French Guiana 2008-2015. BMC Psychiatry. 2018 Apr 11;18(1):99. doi: 10.1186/s12888-018-1670-6.

  • Elias B, Mignone J, Hall M, Hong SP, Hart L, Sareen J. Trauma and suicide behaviour histories among a Canadian indigenous population: an empirical exploration of the potential role of Canada's residential school system. Soc Sci Med. 2012 May;74(10):1560-9. doi: 10.1016/j.socscimed.2012.01.026. Epub 2012 Mar 6.

  • Diehl EE, Langdon EJ, Dias-Scopel RP. [The contribution of indigenous community health workers to special healthcare for Brazilian indigenous peoples]. Cad Saude Publica. 2012 May;28(5):819-31. doi: 10.1590/s0102-311x2012000500002. Portuguese.

  • Chandler, M. J., & Lalonde, C. (1998). Cultural Continuity as a Hedge against Suicide in Canada's First Nations. Transcultural Psychiatry, 35(2), 191-219. https://doi.org/10.1177/136346159803500202

    RESULT
  • Burn H, Black J, Harwood M, Gordon I, Burnett AM, Hamm LM, Evans J, Ramke J. Eye care delivery models to improve access to eye care for Indigenous people in high-income countries: protocol for a scoping review. BMJ Open. 2019 Jul 29;9(7):e029214. doi: 10.1136/bmjopen-2019-029214.

  • Agudelo-Hernandez F, Amaya NV, Cardona M. Suicide in a Colombian indigenous community: Beyond mental illness. Int J Soc Psychiatry. 2023 Dec;69(8):1986-1995. doi: 10.1177/00207640231183922. Epub 2023 Jun 30.

Related Links

MeSH Terms

Conditions

Mental DisordersSuicide Prevention

Condition Hierarchy (Ancestors)

SuicideSelf-Injurious BehaviorBehavioral SymptomsBehavior

Study Officials

  • Mathieu Nacher, MD, PhD

    Centre Hospitalier de Cayenne, Inserm CIC 1424 Guyane-Amazonie

    STUDY DIRECTOR

Central Study Contacts

Cassio De Figueiredo Azze, MCs

CONTACT

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
OTHER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 2, 2026

First Posted

September 9, 2026

Study Start

September 1, 2026

Primary Completion (Estimated)

August 30, 2029

Study Completion (Estimated)

August 30, 2029

Last Updated

September 9, 2026

Record last verified: 2026-08

Locations