The Efficacy of High-Intensity Focused Ultrasound Therapy on Adenomyosis

NCT07808034 | Not Yet Recruiting DMC

• 1 other identifier: 114309-E
• Study Type: observational
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

To assess the efficacy of High-Intensity Focused Ultrasound on adenomyosis

Conditions

Adenomyosis of Uterus

Keywords

adenomyosis; lower urinary tract symptoms; sexual dysfunction; gastrointestinal symptoms

Outcome Measures

Primary Outcomes (1)

• Dysmenorrhea

  The changes of VAS scores of dysmenorrhea

  6 months

Secondary Outcomes (6)

• Menorrhagia

  6 months

• Overactive bladder symptoms

  6 months

• Female sexual function

  6 months

• Bowel incontinence

  6 months

• Overall condition of dysmenorrhea

  6 months

Study Arms (1)

Adenomyosis

adenomyosis of the uterus

Procedure: High Intensity Focused Ultrasound

Interventions

High Intensity Focused Ultrasound PROCEDURE

MRI guided High Intensity Focused Ultrasound

Adenomyosis

Eligibility Criteria

• Age: 18 Years+
• Gender Eligibility Details: Female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with symptomatic uterine adenomyosis:

You may qualify if:

• The patient must be at least 18 years old.
• Adenomyosis: There must be several dark areas on at least one side of the uterine wall; the uterine wall must be thickened; in addition, the thickened uterine wall must have a nonhomogeneous structure; and clinically, there must be dysmenorrhea or menorrhagia.

You may not qualify if:

• The patient currently has an acute lower urinary tract infection or intestinal inflammation.
• The patient has previously undergone bladder or urethral surgery.
• The patient has a history of urinary tract stones or tumors.

Sponsors & Collaborators

• Far Eastern Memorial Hospital: lead

Study Sites (1)

Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital

Banqiao District, New Taipei, 22050, Taiwan

Location

MeSH Terms

Conditions

Adenomyosis; Lower Urinary Tract Symptoms; Sexual Dysfunction, Physiological

Condition Hierarchy (Ancestors)

Uterine Diseases; Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases; Urological Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Chief of Department of Obstetrics and Gynecology

Study Record Dates

• First Submitted: September 3, 2026
• First Posted: September 8, 2026
• Study Start: September 16, 2026
• Primary Completion (Estimated): December 31, 2028
• Study Completion (Estimated): December 31, 2028
• Last Updated: September 8, 2026

Record last verified: 2026-09

Locations

TW (1)