Presurgical Illustration and Psychological Stress in Mandibular Third Molar Surgery

NCT07803510 | Recruiting

• 1 other identifier: DU:0240521008
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this clinical trial is to evaluate the influence of presurgical patient's diagrammatic illustration of mandibular third molar (Wisdom tooth) surgery on degrees of psychological stress.

Conditions

Psychological Stress

Keywords

Psychological Stress; Emotional Stress; Salivary Cortisol; Third Molar Extraction

Outcome Measures

Primary Outcomes (1)

• Salivary Cortisol Level (in ng/mL)

  Amount of salivary cortisol found in patients' saliva is considered directly proportional to degree of psychological stress.

  45 minutes before surgery, and 30 minutes after surgery.

Secondary Outcomes (1)

• Duration of Surgery (in minutes)

  Same time of surgery

Study Arms (2)

Control Group (No Presurgical Illustration)

NO INTERVENTION

Patients in this group will have their mandibular third molar surgery done without having prior exposure to presurgical diagrammatic illustration for their surgery.

Study Group (Presurgical Illustration)

ACTIVE COMPARATOR

Patients in this group will have their mandibular third molar surgery done after having prior exposure to presurgical diagrammatic illustration for their surgery.

Other: Presurgical Diagrammatic Illustration for Mandibular Third Molar Surgery

Interventions

Presurgical Diagrammatic Illustration for Mandibular Third Molar Surgery OTHER

The handling surgeon will show the patient (in the study group) a diagrammatic illustration for surgical steps of mandibular third molar extraction. This diagrammatic illustration includes flap raising, bone guttering, coronal and radicular tooth sectioning, and flap closure.

Study Group (Presurgical Illustration)

Eligibility Criteria

• Age: 18 Years - 32 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Healthy patients (American Society of Anesthesiologists Class I),
• Patients demanding extraction of their mandibular third molar,
• Mandibular third molars requiring flap raising, bone removal, coronal and radicular sectioning (Modified Parant Scale Class IV),
• Patients accepting their saliva sampling prior to and after surgery.

You may not qualify if:

• Acutely painful mandibular third molars on clinical examination,
• Pericoronal and/or active periapical and/or active periodontal pathologies on clinical and radiographic examinations,
• Patients using steroids,
• Psychiatric patients,
• Smokers,
• Pregnant patients, and/or those observing their menstruation,
• Patients with conditions of altered cortisol secretion (such as Addison's disease, Cushing's syndrome, and congenital adrenal hyperplasia),
• Patients with altered secretion of saliva (such as due to using atropine, calcium channel blockers, antidepressants, antihistamines, Sjogren's syndrome, and radiotherapy).
• Patients who are overtly anxious about dental treatment (scoring \>19 on the Modified Dental Anxiety Scale).

Sponsors & Collaborators

• Delta University for Science and Technology: lead

Study Sites (1)

Department of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Delta University for Science and Technology

Al Mansurah, Addakahlyia, 35516, Egypt

RECRUITING

MeSH Terms

Conditions

Stress, Psychological

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior

Study Officials

• Mohammad Abdelhamid, PhD

  Department of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Delta University for Science and Technology

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Mohammad Abdelhamid, PhD

CONTACT

00201002285659; hamidsurgeon@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Masking Details: Both the participant and the surgeon are not blinded to the study predictor variable as they both witness the presurgical illustration (introduced to the study group). The laboratory chemist that will analyze the salivary cortisol is blinded to both arms. This means that the chemist does not know whether the saliva sample is drawn from a patient in the control or the study groups.
• Purpose: SCREENING
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 31, 2026
• First Posted: September 3, 2026
• Study Start: September 5, 2026
• Primary Completion (Estimated): November 1, 2026
• Study Completion (Estimated): November 1, 2026
• Last Updated: September 9, 2026

Record last verified: 2026-08

Locations

EG (1)