Brief Summary

Many people with long-term health conditions require regular blood tests to monitor their disease or medications. These blood tests are usually performed by taking blood from a vein during a hospital or clinic appointment. This can be inconvenient, time-consuming and difficult for some people, particularly those who live far from hospital, have reduced mobility, require frequent tests, or experience anxiety about attending healthcare settings or having blood taken. Capillary blood sampling devices allow people to collect a small blood sample themselves, usually from the upper arm or fingertip, which can then be sent to a laboratory by post. These devices have shown promising results for some blood tests, but there is insufficient evidence of which tests remain accurate when samples are collected at home, posted to the laboratory and subjected to postage conditions and delayed analysis. The CAPSICUM study will compare blood samples collected using patient-operated capillary sampling devices with routine venous blood samples already being taken as part of participants' usual clinical care. We will investigate whether a wide range of blood tests produce similar results using both methods and assess how delayed analysis, postal transport and home collection affect test accuracy. Participants will attend only one study visit, which will take place during a routine clinic appointment. Some participants will also be invited to collect an additional blood sample at home and return it by post, and to complete a brief questionnaire about their experience. The findings from this study will help identify which blood tests can be safely monitored using home capillary blood sampling. This could improve access to blood monitoring, reduce unnecessary hospital visits, make monitoring more convenient for patients, and support the development of safe, evidence-based remote monitoring pathways within the NHS.

Trial Health

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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment

1,000

participants targeted

Target at P75+ for all trials

Timeline

37mo left

Started Oct 2026

Typical duration for all trials

Status

not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

3 years study duration

First Submitted

Initial submission to the registry

August 28, 2026

Completed

6 days until next milestone

First Posted

Study publicly available on registry

September 3, 2026

Completed

28 days until next milestone

Study Start

First participant enrolled

October 1, 2026

Completed

3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2029

Expected

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2029

Last Updated

September 3, 2026

Status Verified

August 1, 2026

Enrollment Period

3 years

First QC Date

August 28, 2026

Last Update Submit

August 28, 2026

Conditions

Chronic Kidney Disease Autoimmune Diseases Solid Organ Transplant Recipients

Outcome Measures

Primary Outcomes (1)

For each pre-defined analyte, the mean difference and 95% limits of agreement between paired capillary and venous blood sample results under immediate analysis conditions, assessed against predefined clinically acceptable limits of agreement.
From enrollment to end of study visit 1