Evaluation of Functional Disability in Rheumatoid Arthritis Patients

NCT07801261 | Not Yet Recruiting

• 1 other identifier: Soh-Med-26-7-25MS
• Study Type: observational
• Target: 150
• Locations: 0 countries
• Sites: N/A

Brief Summary

Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune inflammatory disease that mainly affects the joints and periarticular soft tissues. Accurate monitoring of disease activity is a cornerstone of the treat-to-target approach in Rheumatoid arthritis.

Conditions

Rheumatoid Arthritis (RA)

Outcome Measures

Primary Outcomes (1)

• To evaluate the performance of Rheumatoid Arthritis Impact of Disease (RAID) questionnaire in detecting disease flares in Rheumatoid arthritis patients and to compare it with other disease activity indices.

  1 year

Study Arms (2)

rheumatoid arthritis established patients

control group of non rheumatoid patients

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

This study will include 100 established Rheumatoid arthritis (RA) patients according the 2010 ACR/EULAR classification criteria for RA, who will be recruited from Rheumatology and Rehabilitation department at Sohag university hospital, in addition to 50 controls will be matched for sex, age, and level of schooling

You may qualify if:

• Patients fulfill the 2010 ACR/EULAR classification criteria of Rheumatoid arthritis is based on the confirmed presence of synovitis in at least one joint, absence of an alternative diagnosis better explaining the synovitis, and achievement of a total score of 6 or greater (of a possible 10) from the individual scores in four domains :
• number and site of involved joints (range 0-5)
• serological abnormality (range 0-3)
• elevated acute-phase response (range 0-1)
• symptom duration (two levels; range 0-1).
• Age above 18 years old.
• Patient cooperative and can answer questions

You may not qualify if:

• Other rheumatologic or collagen diseases.
• Age below 18 years and above 65 years.
• Uncooperative patients.

Sponsors & Collaborators

• Sohag University: lead

MeSH Terms

Conditions

Arthritis, Rheumatoid

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Connective Tissue Diseases; Skin and Connective Tissue Diseases; Autoimmune Diseases; Immune System Diseases

Central Study Contacts

Rania Abudief Mohamed

CONTACT

00201015166578; rania8abudief@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident

Study Record Dates

• First Submitted: August 30, 2026
• First Posted: September 3, 2026
• Study Start: August 20, 2026
• Primary Completion (Estimated): January 20, 2027
• Study Completion (Estimated): August 20, 2027
• Last Updated: September 3, 2026

Record last verified: 2026-07