Effects of a Mobile Game in Menopausal Women

NCT07800793 | Not Yet Recruiting

• 1 other identifier: E-10840098-50.04-5261
• Study Type: interventional
• Target: 82
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to evaluate the effect of a mobile game-based cognitive intervention on brain fog and psychological well-being in menopausal women aged 45-55 years. The main questions it aims to answer are: Are Brain Fog Scale scores lower among women in the mobile game intervention group compared with women in the control group? Are Warwick-Edinburgh Mental Well-Being Scale scores higher among women in the mobile game intervention group compared with women in the control group? Do women participating in the mobile game intervention demonstrate greater reductions in Brain Fog Scale scores and greater improvements in Warwick-Edinburgh Mental Well-Being Scale scores after the intervention compared with their baseline measurements? Researchers will compare participants receiving the mobile game-based cognitive intervention with participants receiving routine follow-up only to determine the effectiveness of the intervention on brain fog and psychological well-being. Participants will: Complete baseline assessments using the Brain Fog Scale and the Warwick-Edinburgh Mental Well-Being Scale. Be randomly assigned to either the intervention group or the control group. Use the cognitive training mobile game for 15 minutes per day, 5 days per week, for 6 weeks if assigned to the intervention group. Receive routine follow-up only if assigned to the control group. Complete post-intervention assessments at the end of the 6-week study period.

Conditions

Menopause; Brain Fog; Psychological Well-being

Keywords

menopause; brain fog; psychological well-being

Outcome Measures

Primary Outcomes (1)

• Brain fog

  Change in Brain Fog Scale total score from baseline to post-intervention. The Brain Fog Scale is a 30-item instrument assessing cognitive, physical, and psychological symptoms of brain fog. Total scores range from 30 to 150, with higher scores indicating greater brain fog severity (worse outcome).

  Baseline and Week 6

Secondary Outcomes (1)

• Change in Warwick-Edinburgh Mental Well-Being

  Baseline and Week 6

Study Arms (2)

Menopause Mobile Game Intervention

EXPERIMENTAL

Participants will use a mobile game developed to address brain fog symptoms during menopause.

Behavioral: Menopause Mobile Game

Routine Care Control

NO INTERVENTION

Participants will receive routine care and will not use the mobile game during the study period.

Interventions

Menopause Mobile Game BEHAVIORAL

Participants in the intervention group will use a mobile game specifically designed for menopausal women to support cognitive functioning. The game includes interactive exercises and activities targeting attention, memory, processing speed, and other cognitive skills. Participants will use the mobile game throughout the intervention period in addition to routine care.

Also known as: Menopause Education and Self-Management Mobile Game

Menopause Mobile Game Intervention

Eligibility Criteria

• Age: 45 Years - 55 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Women aged 45-55 years
• Able to read and write in Turkish
• Able to use a smartphone (Android or iOS)
• Amenorrhea for at least 12 months
• Willing to participate and provide written informed consent

You may not qualify if:

• Diagnosis of serious neurological disorders such as dementia, Alzheimer's disease, epilepsy, or multiple sclerosis
• Diagnosis of severe psychiatric disorders such as major depression, bipolar disorder, or schizophrenia
• Regular use of medications that may significantly affect cognitive function, including antiepileptics, antiparkinsonian drugs, antipsychotics, or antidepressants
• Participation in cognitive training, memory training, or a similar digital intervention within the last 6 months
• Visual, auditory, or motor impairments that would prevent the use of the mobile application
• Participants scoring within the lowest 25% quartile (Q1) on the Brain Fog Scale

Sponsors & Collaborators

• Medipol University: lead
• Istanbul University - Cerrahpasa: collaborator

Study Sites (1)

İstanbul Medipol University Mega Hospital

Istanbul, Mrs, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Mental Fatigue; Psychological Well-Being

Condition Hierarchy (Ancestors)

Fatigue; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavioral Symptoms; Behavior; Personal Satisfaction

Study Officials

• Nazire BAHAR

  Istanbul Universitesi-Cerrahpasa

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Nazire BAHAR

CONTACT

905540070907; naziresel@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer

Study Record Dates

• First Submitted: August 30, 2026
• First Posted: September 2, 2026
• Study Start (Estimated): October 15, 2026
• Primary Completion (Estimated): September 15, 2027
• Study Completion (Estimated): December 15, 2027
• Last Updated: September 17, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)