NCT07800234

Brief Summary

Establishing a National Egyptian HLH Registry (NEHR)

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
26mo left

Started Mar 2024

Longer than P75 for all trials

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress55%
Mar 2024Dec 2028

Study Start

First participant enrolled

March 2, 2024

Completed
2.5 years until next milestone

First Submitted

Initial submission to the registry

August 30, 2026

Completed
3 days until next milestone

First Posted

Study publicly available on registry

September 2, 2026

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2028

Expected
11 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2028

Last Updated

September 2, 2026

Status Verified

August 1, 2026

Enrollment Period

3.8 years

First QC Date

August 30, 2026

Last Update Submit

August 30, 2026

Conditions

HLHHemophagocytic Lymphohistiocytoses

Outcome Measures

Primary Outcomes (1)

  • A nationwide HLH map

    Establish a nationwide map for children with presumed diagnosis of HLH

    2 years

Study Arms (1)

Hemophagocytic lymphohistiocytosis (HLH)

Children diagnosed with Hemophagocytic lymphohistiocytosis (HLH)

Eligibility Criteria

AgeUp to 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Patients diagnosed with hlh

You may qualify if:

  • patients diagnosed with hlh

You may not qualify if:

  • adults

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Faculty of Medicine Pediatric Hematology Oncology Department

Cairo, 11566, Egypt

RECRUITING

Faculty of medicine ain shams university

Cairo, Egypt

ACTIVE NOT RECRUITING

MeSH Terms

Conditions

Lymphohistiocytosis, Hemophagocytic

Condition Hierarchy (Ancestors)

Histiocytosis, Non-Langerhans-CellHistiocytosisLymphatic DiseasesHemic and Lymphatic Diseases

Central Study Contacts

Iman Ragab Prof of Pediatrics, Ain Shams University, Professor

CONTACT

+20 1002550680hragab68@hotmail.com

Fatma Ebeid Professor of pediatrics, Ain Shams University, Professor

CONTACT

+201095569596

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
OTHER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

August 30, 2026

First Posted

September 2, 2026

Study Start

March 2, 2024

Primary Completion (Estimated)

January 1, 2028

Study Completion (Estimated)

December 1, 2028

Last Updated

September 2, 2026

Record last verified: 2026-08

Data Sharing

IPD Sharing
Will not share

Locations

EG(2)