NCT07798167

Active Not Recruiting

Tuberculosis Sentinel Research Network (TB-SRN)

Centre for Infectious Disease Research in Zambia Source

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Other study identifiers

Sponsor study identifier

IeDea TB-SRN 2538-2022

Study Type

observational

Actual enrollment (reported)

374

Locations

1 country

Sites

1

Timeline

Study Start

September 15, 2022

Actual (reported)

Primary Completion

December 22, 2026

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Study Completion

April 2027

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Brief Summary

The overarching objective/aim of the study is to assess pulmonary TB treatment and longer-term outcomes among people with and without HIV in African population in order to inform policy and practice around TB treatment and create a platform for additional TB research in Zambia

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: active not recruiting
Actual enrollment (reported): 374 participants
Study completion date: April 2027
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
September 15, 2022
Actual (reported)
First Submitted
August 18, 2026
Actual (reported)
First Posted
September 1, 2026
Actual (reported)
Primary Completion
December 22, 2026
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
April 2027
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.

Last Updated: October 13, 2026
Status Verified: October 2026
Last Update Submitted: October 7, 2026

Conditions

Tuberculosis

Keywords

TB-Transmission

Outcome Measures

Primary Outcomes (1)

Proportion of participants achieving successful pulmonary tuberculosis treatment outcome at the end of TB treatment
The proportion of participants who achieve a successful pulmonary tuberculosis treatment outcome at the end of the TB treatment period. Treatment success will be defined according to the study-prespecified TB treatment outcome definitions and will be compared between participants with and without HIV.
4 YEARS

Eligibility Criteria

Age15 Years - 99 Years

Sexall

Healthy VolunteersNo

Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

Sampling MethodProbability Sample

Study Population

553

You may qualify if:

\. Be ≥15 years of age

Sponsors & Collaborators

Centre for Infectious Disease Research in Zambia
Otherlead

Study Sites (1)

Chawama and Kanyama General Hospitals

Lusaka, Lusaka Province, 10101, Zambia

MeSH Terms

Conditions

Tuberculosis

Condition Hierarchy (Ancestors)

Mycobacterium InfectionsActinomycetales InfectionsGram-Positive Bacterial InfectionsBacterial InfectionsBacterial Infections and MycosesInfections

Enrollment

374 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: CROSS SECTIONAL
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

August 18, 2026

First Posted

September 1, 2026

Study Start

September 15, 2022

Actual (reported)

Assessing Diagnostics At Point-of-care for Tuberculosis

Not ApplicableRecruiting

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Early Risk Assessment in Household Contacts (≥10 Years) of TB Patients by New Diagnostic Tests in 3 African Countries

Unknown

NCT03639038

Tuberculosis Diagnosis by Flow Cytometry

Withdrawn

NCT05259254

Effectiveness Of Mobile Application To Improve Adherence To Tuberculosis Treatment

Not ApplicableUnknown

NCT05964842

Using SMS Reminders, Phone Calls and Money Incentives to Enhance Linkage to Care of Presumptive TB Patients in Uganda

Not ApplicableCompleted

NCT06141148

Clinical Presentation, and Treatment Outcomes in Tuberculous Patients in Sohag Governorate

Unknown

Clinically diagnosed pulmonary TB and initiated/to be initiated on anti-TB treatment, as determined by medical providers through standard of care, on the basis of either.

Microbiologically confirmed pulmonary TB based on sputum or other respiratory samples with either

You may not qualify if:

Have plans to follow-up for TB care at a site distant from the enrollment site, imminent plans to move from his/her current area of residence, or plans to return to a distant area of residence, which would interfere with the participant's ability to complete all study visits (through the 12-month post-treatment visit).
\. Received \>1 week of TB treatment within the prior 30 days, excluding TB preventive therapy
\. Have substantial cognitive impairment that in the opinion of the site investigator or designee may interfere with the ability to give reliable informed consent

Contact the study team to confirm eligibility.

Primary Completion

December 22, 2026

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Study Completion

April 2027

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Last Updated

October 13, 2026

Record last verified: 2026-10

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT07798167
Data provider: ClinicalTrials.gov
Source updated: 2026-10-13
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:21:10 UTC

Locations

ZM(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations