Fucoidan(Seaweed) Based Gel Around Osseous Defects

NCT07793851 | Completed

• 1 other identifier: KCDSHEC/IP/2025/44
• Study Type: observational
• Target: 5
• Locations: 1 country
• Sites: 1

Brief Summary

The current study is a prospective case series study to evaluate the effect of Fucoidan gel around osseous defects to assess the wound healing and bone regeneration

Conditions

Wound Healing; Bone Regeneration

Outcome Measures

Primary Outcomes (1)

• wound healing following placement of fucoidan gel

  Landry, Turnbull and Howley wound healing index

  7th day,14th day, 21st day, 1 month, at 3months and 6 months

Secondary Outcomes (1)

• crestal bone level

  baseline, 3month and 6 month

Study Arms (1)

placement of fucoidan gel in osseous defects

Drug: Fucoidan extracted from F. Vesiculosus placement of fucoidan gel in osseous defects such as intrabony defect, compromised bone support

Eligibility Criteria

• Age: 25 Years - 55 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

All the patients who meet the eligible criteria will undergo Scaling and root planning (SRP) as a part of Phase I therapy. Patients with ≥6mm probing sites will undergo surgical therapy, patients presenting with different osseous defects will be treated with Fucoidan gel. A total of 5 samples will be allotted to different defects

You may qualify if:

• Systemically healthy patients between 25 to 55 years.
• Stage II/III and Grade B periodontitis patient.
• Osseous defects (intra bony defects, compromised bone support and around dental implants)

You may not qualify if:

• Patients with systemic diseases.
• Smokers.
• Patients under anticoagulant therapy.
• Patients under bisphosphonates.
• Pregnant and lactating women

Sponsors & Collaborators

• Krishnadevaraya College of Dental Sciences & Hospital: lead

Study Sites (1)

Krishnadevaraya college of dental sciences and hospital

Bangalore, Karnataka, 562157, India

Location

Study Officials

• DR .Prabhuji MLV, MDS

  Krishnadevaraya college of dental sciences and hospital

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 24, 2026
• First Posted: August 31, 2026
• Study Start: June 11, 2025
• Primary Completion: October 11, 2025
• Study Completion: June 30, 2026
• Last Updated: August 31, 2026

Record last verified: 2026-08

Locations

IN (1)