Outcomes of Intra-articular Steroid Injection Via Ultrasound Guidance Versus Fluoroscopic Guidance in the Sacroiliac Joint in Patients With Sacroiliitis

NCT07791108 | Not Yet Recruiting

• 1 other identifier: 48.ERC/FMU/2025-26/339
• Study Type: interventional
• Target: 176
• Locations: 1 country
• Sites: 1

Brief Summary

Sacroiliitis is a common cause of low back and buttock pain. Intra-articular steroid injection of the sacroiliac joint can provide pain relief and functional improvement. This randomized controlled trial aims to compare the outcomes of ultrasound-guided versus fluoroscopic-guided sacroiliac joint steroid injections in patients with sacroiliitis. The study will evaluate procedural success, pain reduction, and functional improvement using the Visual Analogue Scale (VAS) and Oswestry Disability Index (ODI) at follow-up intervals.

Conditions

Sacroiliitis

Keywords

Sacroillitis, Triamcinolone

Outcome Measures

Primary Outcomes (1)

• Procedural success rate of sacroiliac joint injection

  Successful intra-articular deposition of steroid in the sacroiliac joint confirmed by the respective imaging guidance modality (ultrasound or fluoroscopy).

  During the procedure

Secondary Outcomes (1)

• Oswestry Disability Index (ODI) Score

  Baseline, 2 weeks, 1 month, and 3 months after the procedure

Study Arms (2)

Ultrasound-guided SI Joint Injection

EXPERIMENTAL

Participants will receive sacroiliac joint steroid injection under ultrasound guidance using 40 mg triamcinolone acetonide mixed with 1 mL 0.25% bupivacaine.

Procedure: Ultrasound-guided intra-articular steroid injection

Fluoroscopic-guided SI Joint Injection

ACTIVE COMPARATOR

Participants will receive sacroiliac joint steroid injection under fluoroscopic guidance with contrast confirmation followed by the same steroid-bupivacaine injection.

Procedure: Ultrasound-guided intra-articular steroid injection

Interventions

Ultrasound-guided intra-articular steroid injection PROCEDURE

Participants will receive intra-articular sacroiliac joint steroid injection under ultrasound guidance. A needle will be advanced under real-time ultrasound guidance to the sacroiliac joint, and 40 mg triamcinolone acetonide mixed with 1 mL 0.25% bupivacaine will be injected.

Also known as: Ultrasound-guided SI Joint Injection

Fluoroscopic-guided SI Joint Injection; Ultrasound-guided SI Joint Injection

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 18-70 years
• Both sexes
• Clinical diagnosis of sacroiliitis

You may not qualify if:

• Prior SI joint injection in the past 12 months
• Contraindication to corticosteroid injection (systemic infection, local infection, bleeding diathesis, uncontrolled diabetes with HbA1c \>9%, allergy to contrast or steroid)
• Radicular or neurogenic pain attributable to lumbar spine or hip pathology
• Pregnancy or breastfeeding
• Severe osteoarthritis or fusion of the SI joint on imaging
• Systemic rheumatologic disease requiring systemic biologic therapy (unless stable for \>6 months)

Sponsors & Collaborators

• Allied Hospital Faisalabad: lead

Study Sites (1)

Allied Hospital Faisalabad

Faisalābad, Punjab Province, 38000, Pakistan

Location

MeSH Terms

Conditions

Sacroiliitis

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases

Central Study Contacts

Dr.Tahir Aslam Tahir, MBBS, FCPS Orthopedics

CONTACT

+923004499924; tahiraslam398@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr Tahir Aslam

Model Details: Participants will be randomly assigned in a 1:1 ratio to receive intra-articular sacroiliac joint steroid injection either under ultrasound guidance or fluoroscopic guidance. Outcomes will be compared between both groups.

Study Record Dates

• First Submitted: August 25, 2026
• First Posted: August 27, 2026
• Study Start: August 25, 2026
• Primary Completion (Estimated): October 15, 2026
• Study Completion (Estimated): October 25, 2026
• Last Updated: August 27, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)