Activia Kefir Consumption in Real-world Setting

NCT07790666 | Not Yet Recruiting

• 1 other identifier: 25REX0093320
• Study Type: observational
• Target: 550
• Locations: 1 country
• Sites: 3

Brief Summary

The study aims at generating first real-world insights into how consumers perceive the benefits of consuming Activia Kefir on their digestive wellbeing, overall wellbeing, and to explore its potential effects on the gut microbiome.

Conditions

Kefir Usual Consumers and New Kefir Consumers

Keywords

Digestive wellbeing; Quality of life; Gut Microbiome

Outcome Measures

Primary Outcomes (4)

• Gastrointestinal (GI)-wellbeing (single-item question)

  Difference between after consumption and baseline

  After 2 weeks of study product consumption

• Stool consistency (Bristol stool scale, single-item)

  Difference between after consumption and baseline

  After 2 weeks of study product consumption

• Stool frequency (number of stools/week, single-item)

  Difference between after consumption and baseline

  After 2 weeks of study product consumption

• Digestive symptoms frequency questionnaire (DSFQ, frequency of 4 symptoms: abdominal pain/discomfort, bloating, flatulence, borborygmi)

  Difference between after consumption and baseline

  After 2 weeks of study product consumption

Secondary Outcomes (3)

• PROMIS global health questionnaire (10-item, includes questions about emotional state fatigue, pain, general health, quality of life, physical health, mental health, satisfaction social activities, usual activities, and everyday physical activities)

  After 2 weeks of study product consumption

• WHO wellbeing questionnaire (5-items, includes questions about cheerful/good spirits, calm/relaxed, active/vigorous, feeling fresh/rested, daily life with things that interest me)

  After 2 weeks of study product consumption

• Perceived resilience (using the 2-item Connor-Davidson Resilience Scale (CD-RISC)-2)

  After 2 weeks of study product consumption

Study Arms (1)

Consumers of Activia Kefir

Other: Commercialized dairy product consumption and stool samples collection

Interventions

Commercialized dairy product consumption and stool samples collection OTHER

Consumption of 280 mL (1 bottle) Activia Kefir drinkable per day during the two-weeks study period and collection of 2 stools samples using a collection kit at participant's home (before and after product consumption)

Consumers of Activia Kefir

Eligibility Criteria

• Age: 18 Years - 90 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study will include male and female participants aged 18 years and older at the time of screening. Both current (Activia) kefir consumers and individuals who are new to (Activia) kefir consumption will be eligible for participation.

You may qualify if:

• Males and females aged 18 years and older at the time of screening;
• Willingness to consume Activia Kefir and complete the requested questionnaires;
• Living in the designated locations in Spain, able to read and write in Spanish;
• Have a personal electronic device compatible and connectable to internet (i.e., computer, laptop, smartphone) to fill the questionnaires;
• Signed informed consent.

You may not qualify if:

• People that currently participate in another study with (dairy) investigational or marketed products;
• Severely immunocompromised individuals (e.g., post-transplant, advanced HIV/AIDS, undergoing chemotherapy);
• Individuals with known allergies or intolerances to product ingredients. For lactose maldigestion, kefir may improve tolerance, so individuals who are aware of their condition and still wish to participate can be included.

Sponsors & Collaborators

• Danone Global Research & Innovation Center: lead

Study Sites (3)

Mmr Research Worlwide B.V

Barcelona, Spain

Location

Mmr Research Worlwide B.V

Madrid, Spain

Location

Mmr Research Worlwide B.V

Valencia, Spain

Location

Biospecimen

Retention: SAMPLES WITH DNA

Stool samples from general population. Stool samples are collected for gut microbiota analysis: no human genetic analysis is performed (bacterial DNA only).

Central Study Contacts

Danone Global Research & Innovation Center

CONTACT

+33 (0)1 69 35 70 00; register.clinicalresearchnutricia@danone.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 24, 2026
• First Posted: August 27, 2026
• Study Start (Estimated): September 1, 2026
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: August 27, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share

Locations

ES (3)